Neuromuscular junction dysfunction in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal neurological disorder characterized by
progressive degeneration of motor neurons leading to skeletal muscle denervation. Earlier …
progressive degeneration of motor neurons leading to skeletal muscle denervation. Earlier …
[HTML][HTML] Nutritional and metabolic factors in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that is
classically thought to impact the motor system. Over the past 20 years, research has started …
classically thought to impact the motor system. Over the past 20 years, research has started …
Comprehensive research on past and future therapeutic strategies devoted to treatment of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a rapidly debilitating fatal neurodegenerative disorder,
causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS …
causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS …
TDP-43 dysregulation and neuromuscular junction disruption in amyotrophic lateral sclerosis
S Lépine, MJ Castellanos-Montiel… - Translational …, 2022 - Springer
Amyotrophic lateral sclerosis (ALS) is a disease characterized by upper and lower motor
neuron (MN) loss with a signature feature of cytoplasmic aggregates containing TDP-43 …
neuron (MN) loss with a signature feature of cytoplasmic aggregates containing TDP-43 …
Skeletal muscle in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS), the major adult-onset motor neuron disease, has been
viewed almost exclusively as a disease of upper and lower motor neurons, with muscle …
viewed almost exclusively as a disease of upper and lower motor neurons, with muscle …
Skeletal muscle in ALS: an unappreciated therapeutic opportunity?
S Scaricamazza, I Salvatori, A Ferri, C Valle - Cells, 2021 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the
selective degeneration of upper and lower motor neurons and by the progressive weakness …
selective degeneration of upper and lower motor neurons and by the progressive weakness …
[HTML][HTML] New Insights for nicotinamide: Metabolic disease, autophagy, and mTOR
K Maiese - Frontiers in bioscience (Landmark edition), 2020 - ncbi.nlm.nih.gov
Metabolic disorders, such as diabetes mellitus (DM), are increasingly becoming significant
risk factors for the health of the global population and consume substantial portions of the …
risk factors for the health of the global population and consume substantial portions of the …
Cystatin C based estimation of chronic kidney disease and amyotrophic lateral sclerosis in the ALS registry Swabia: associated risk and prognostic value
G Nagel, D Kurz, RS Peter, A Rosenbohm, W Koenig… - Scientific Reports, 2023 - nature.com
Kidney function as part of metabolic changes could be associated with amyotrophic lateral-
sclerosis (ALS). We investigated the associations between estimated chronic kidney disease …
sclerosis (ALS). We investigated the associations between estimated chronic kidney disease …
Nicotinamide: oversight of metabolic dysfunction through sirt1, mtor, and clock genes
K Maiese - Current neurovascular research, 2020 - ingentaconnect.com
Metabolic disorders that include diabetes mellitus present significant challenges for
maintaining the welfare of the global population. Metabolic diseases impact all systems of …
maintaining the welfare of the global population. Metabolic diseases impact all systems of …
Hypothalamus and amyotrophic lateral sclerosis: potential implications in sleep disorders
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects
both motor and non-motor functions, including sleep regulation. Emerging evidence …
both motor and non-motor functions, including sleep regulation. Emerging evidence …