Protein nanoparticles: promising platforms for drug delivery applications

A Jain, SK Singh, SK Arya, SC Kundu… - … Biomaterials Science & …, 2018 - ACS Publications
The development of drug delivery systems using nanoparticles as carriers for small and
large therapeutic molecules remains a rapidly growing area of research. The advantages of …

Recent advances in biopolymer-based formulations for wound healing applications

DN Moholkar, PS Sadalage, D Peixoto… - European Polymer …, 2021 - Elsevier
Since decades, the field of wound healing has gained immense attention from the
researchers worldwide. The ultimate goal is to develop effective techniques that can speed …

The neuropeptide calcitonin gene-related peptide alpha is essential for bone healing

J Appelt, A Baranowsky, D Jahn, T Yorgan, P Köhli… - …, 2020 - thelancet.com
Background Impaired fracture healing represents an ongoing clinical challenge, as
treatment options remain limited. Calcitonin gene-related peptide (CGRP), a neuropeptide …

Clinically relevant preclinical animal models for testing novel cranio‐maxillofacial bone 3D‐printed biomaterials

LP Hatt, K Thompson, JA Helms… - Clinical and …, 2022 - Wiley Online Library
Bone tissue engineering is a rapidly developing field with potential for the regeneration of
craniomaxillofacial (CMF) bones, with 3D printing being a suitable fabrication tool for patient …

Osteogenic capability of vaterite‐coated nonwoven polycaprolactone scaffolds for in vivo bone tissue regeneration

MS Saveleva, AN Ivanov, JA Chibrikova… - Macromolecular …, 2021 - Wiley Online Library
In current orthopedic practice, bone implants used to‐date often exhibit poor
osteointegration, impaired osteogenesis, and, eventually, implant failure. Actively pursued …

Cell-based therapy in the treatment of musculoskeletal diseases

J Trapana, J Weinerman, D Lee… - Stem cells …, 2024 - academic.oup.com
A limited number of tissues can spontaneously regenerate following injury, and even fewer
can regenerate to a state comparable to mature, healthy adult tissue. Mesenchymal stem …

[HTML][HTML] Role of emerging vitamin K‑dependent proteins: Growth arrest‑specific protein 6, Gla‑rich protein and periostin

H Xiao, J Chen, L Duan, S Li - … journal of molecular …, 2021 - spandidos-publications.com
Vitamin K‑dependent proteins (VKDPs) are a group of proteins that need vitamin K to
conduct carboxylation. Thus far, scholars have identified a total of 17 VKDPs in the human …

Recent trends in bone defect repair and bone tissue regeneration of the two-dimensional material MXene

X Chen, Y Cheng, H Wu - Ceramics International, 2023 - Elsevier
Bone defects have attracted much attention for a long time and seriously affect the function
of the motor system. At present, the application of biological materials and biological …

Fibrin sealant derived from human plasma as a scaffold for bone grafts associated with photobiomodulation therapy

KT Pomini, DV Buchaim, JC Andreo… - International Journal of …, 2019 - mdpi.com
Fibrin sealants derived from human blood can be used in tissue engineering to assist in the
repair of bone defects. The objective of this study was to evaluate the support system formed …

Use of photobiomodulation combined with fibrin sealant and bone substitute improving the bone repair of critical defects

KT Pomini, DV Buchaim, ACC Bighetti, JC Andreo… - Polymers, 2022 - mdpi.com
In this preclinical protocol, an adjunct method is used in an attempt to overcome the
limitations of conventional therapeutic approaches applied to bone repair of large bone …