Significant recent progress in understanding rheumatoid arthritis (RA) pathogenesis has led
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …

Synovial tissue macrophages (STMs) were principally recognized as having a pro-
inflammatory role in rheumatoid arthritis (RA), serving as the main producers of pathogenic …

Next-generation sequencing (NGS) technologies have greatly expanded the size of the
known transcriptome. Many newly discovered transcripts are classified as long noncoding …

The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is an
essential component of the human innate immune system, and is closely associated with …

Background Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that
affects multiple joints and has adverse effects on various organs throughout the body, often …

Objective Rheumatoid arthritis (RA) progression is associated with the balance of T-
regulatory (Treg) and T-helper 17 (Th17) cells, while the role of microRNAs (miRs) in …

MicroRNAs (miRNAs) are a class of regulatory non-coding RNAs that finetune cellular
functions by modulating the stability and abundance of their target mRNAs, thereby …

Background: Heart failure (HF) is a complex clinical syndrome with signs and symptoms
resulting from any structural dysfunction of ventricular filling or blood ejection. miRNAs were …