Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …

ABSTRACT Interleukin 10 (IL-10) is a cytokine with potent anti-inflammatory properties that
plays a central role in limiting host immune response to pathogens, thereby preventing …

Since the discovery of interleukin-10 (IL-10) in the 1980s, a large body of work has led to its
recognition as a pleiotropic immunomodulatory cytokine that affects both the innate and …

The hygiene hypothesis postulates that an environment with a high incidence of infectious
diseases protects against allergic and autoimmune diseases, whereas hygienic …

Interleukin‐10 (IL‐10) has long been recognized to have potent and broad‐spectrum anti‐
inflammatory activity, which has been unequivocally established in various models of …

Allergic diseases are caused by aberrant T-helper-2 immune responses in susceptible
individuals. Both naturally occurring CD4+ CD25+ regulatory T cells and inducible …

We previously reported that human CD4+ Tregs secrete high levels of IL-10 when stimulated
in the presence of dexamethasone and calcitriol (vitamin D3). We now show that following …

Asthma is characterized by T helper cell 2 (Th2) type inflammation, leading to airway
hyperresponsiveness and tissue remodeling. Th2 cell-driven inflammation is likely to …

Interleukin‐10 (IL‐10) is a cytokine with broad anti‐inflammatory properties by its
suppression of both macrophage and dendritic cell function, including antigen‐presenting …

Asthma is a complex chronic inflammatory disease of the airways that involves the activation
of many inflammatory and structural cells, all of which release inflammatory mediators that …