Multifunctional hydrogels based on chitosan, hyaluronic acid and other biological macromolecules for the treatment of inflammatory bowel disease: A review

Y Ouyang, J Zhao, S Wang - International journal of biological …, 2023 - Elsevier
Hydrogel is a three-dimensional network polymer material rich in water. It is widely used in
the biomedical field because of its unique physical and chemical properties and good …

pH sensitive hydrogels in drug delivery: Brief history, properties, swelling, and release mechanism, material selection and applications

M Rizwan, R Yahya, A Hassan, M Yar, AD Azzahari… - Polymers, 2017 - mdpi.com
Improving the safety efficacy ratio of existing drugs is a current challenge to be addressed
rather than the development of novel drugs which involve much expense and time. The …

pH‐responsive polymers for drug delivery: trends and opportunities

J Singh, P Nayak - Journal of Polymer Science, 2023 - Wiley Online Library
Polymer science has applications in biomedical engineering, prosthetics, surgical implants,
and prospective pharmaceutical excipients for drug delivery.“Intelligent or Smart Polymers” …

Targeted delivery of hydrogels in human gastrointestinal tract: A review

Z Yang, DJ McClements, C Li, S Sang, L Chen… - Food …, 2023 - Elsevier
The global demand for healthier food products has led to the introduction of functional foods
fortified with bioactive agents, such as vitamins and nutraceuticals. Many of these bioactive …

Novel in situ forming hydrogel based on xanthan and chitosan re-gelifying in liquids for local drug delivery

J Huang, Y Deng, J Ren, G Chen, G Wang, F Wang… - Carbohydrate …, 2018 - Elsevier
Injectable hydrogels have been an attractive topic in biomaterials. However, during gelation
in vivo, they are easy to disperse due to tissue exudates, thus leading to failure of controlled …

PD‐1/PD‐L1‐dependent immune response in colorectal cancer

Z Payandeh, S Khalili, MH Somi… - Journal of cellular …, 2020 - Wiley Online Library
Colorectal cancer (CRC) is still considered as the third most frequent cancer in the world.
Microsatellite instability (MSI), inflammation, and microRNAs have been demonstrated as …

Starch-based hydrogels as a drug delivery system in biomedical applications

CS Lee, HS Hwang - Gels, 2023 - mdpi.com
Starch-based hydrogels have gained significant attention in biomedical applications as a
type of drug delivery system due to their biocompatibility, biodegradability, and ability to …

Intelligent superabsorbents based on a xanthan gum/poly (acrylic acid) semi-interpenetrating polymer network for application in drug delivery systems

M Hajikhani, MM Khanghahi, M Shahrousvand… - International journal of …, 2019 - Elsevier
In the present study, semi-interpenetrating polymer networks (semi-IPNs) were synthesized
based on crosslinked acrylic acid (AA)/xanthan gum (XG) biopolymer in the presence of N …

Effect of light irradiation on heavy metal adsorption onto microplastics

WH Lin, J Kuo, SL Lo - Chemosphere, 2021 - Elsevier
Microplastics are frequently found in many environmental media. Polypropylene (PP) is one
of the plastics commonly used, resulting in more and more PP fragments in natural waters …

Advancements in hydrogel-based drug delivery systems for the treatment of inflammatory bowel disease: a review

Y Liu, J Huang, S Li, Z Li, C Chen, G Qu, K Chen… - Biomaterials …, 2024 - pubs.rsc.org
Inflammatory bowel disease (IBD) is a chronic disorder that affects millions of individuals
worldwide. However, current drug therapies for IBD are plagued by significant side effects …