Background Regional anaesthesia may reduce the risk of persistent (chronic) pain after
surgery, a frequent and debilitating condition. We compared regional anaesthesia vs …

The literature on cognitive markers in preclinical AD is reviewed. The findings demonstrate
that impairment in multiple cognitive domains is typically observed several years before …

Objective: To determine the relationship between hearing loss and cognitive function as
assessed with a standardized neurocognitive battery. We hypothesized a priori that greater …

Background Participation in leisure activities has been associated with a lower risk of
dementia. It is unclear whether increased participation in leisure activities lowers the risk of …

Background. To investigate the association between hearing loss and cognitive function in a
nationally representative sample of older adults. Methods. We analyzed data from the 1999 …

Objective Whereas cognitive deficits are known to be detectable long before the typical
symptoms of Alzheimer's disease (AD) are evident, previous studies have failed to …

A better knowledge of long-term trajectories of cognitive decline is a central feature of the
study of the process leading to Alzheimer's dementia. Several factors may mitigate such …

Better knowledge of the preclinical phase of Alzheimer's disease would be an important
advance to allow earlier treatment of this ominous disease. This prodromal period was …

In the Baltimore Longitudinal Study of Aging (BLSA), we examined the temporal unfolding of
declining performance on tests of episodic memory (Free Recall on the Free and Cued …

Objective: To examine the extent to which persons with mild cognitive impairment (MCI)
have an increased risk of Alzheimer disease (AD) and a more rapid rate of decline in …