[HTML][HTML] High-throughput proteomics: a methodological mini-review

M Cui, C Cheng, L Zhang - Laboratory investigation, 2022 - Elsevier
Proteomics plays a vital role in biomedical research in the post-genomic era. With the
technological revolution and emerging computational and statistic models, proteomic …

Applications of machine learning in human microbiome studies: a review on feature selection, biomarker identification, disease prediction and treatment

LJ Marcos-Zambrano… - Frontiers in …, 2021 - frontiersin.org
The number of microbiome-related studies has notably increased the availability of data on
human microbiome composition and function. These studies provide the essential material …

Updating the 97% identity threshold for 16S ribosomal RNA OTUs

RC Edgar - Bioinformatics, 2018 - academic.oup.com
Abstract Motivation The 16S ribosomal RNA (rRNA) gene is widely used to survey microbial
communities. Sequences are often clustered into Operational Taxonomic Units (OTUs) as …

Comprehensive survey on hierarchical clustering algorithms and the recent developments

X Ran, Y Xi, Y Lu, X Wang, Z Lu - Artificial Intelligence Review, 2023 - Springer
Data clustering is a commonly used data processing technique in many fields, which divides
objects into different clusters in terms of some similarity measure between data points …

FROGS: find, rapidly, OTUs with galaxy solution

F Escudié, L Auer, M Bernard, M Mariadassou… - …, 2018 - academic.oup.com
Motivation Metagenomics leads to major advances in microbial ecology and biologists need
user friendly tools to analyze their data on their own. Results This Galaxy-supported …

Correlation and association analyses in microbiome study integrating multiomics in health and disease

Y Xia - Progress in molecular biology and translational …, 2020 - Elsevier
Correlation and association analyses are one of the most widely used statistical methods in
research fields, including microbiome and integrative multiomics studies. Correlation and …

A general species delimitation method with applications to phylogenetic placements

J Zhang, P Kapli, P Pavlidis, A Stamatakis - Bioinformatics, 2013 - academic.oup.com
Motivation: Sequence-based methods to delimit species are central to DNA taxonomy,
microbial community surveys and DNA metabarcoding studies. Current approaches either …

Minimum entropy decomposition: unsupervised oligotyping for sensitive partitioning of high-throughput marker gene sequences

AM Eren, HG Morrison, PJ Lescault… - The ISME …, 2015 - academic.oup.com
Molecular microbial ecology investigations often employ large marker gene datasets, for
example, ribosomal RNAs, to represent the occurrence of single-cell genomes in microbial …

OptiClust, an improved method for assigning amplicon-based sequence data to operational taxonomic units

SL Westcott, PD Schloss - MSphere, 2017 - Am Soc Microbiol
Assignment of 16S rRNA gene sequences to operational taxonomic units (OTUs) is a
computational bottleneck in the process of analyzing microbial communities. Although this …

[HTML][HTML] De novo clustering methods outperform reference-based methods for assigning 16S rRNA gene sequences to operational taxonomic units

SL Westcott, PD Schloss - PeerJ, 2015 - peerj.com
Background. 16S rRNA gene sequences are routinely assigned to operational taxonomic
units (OTUs) that are then used to analyze complex microbial communities. A number of …