A Review on the Development of Novel Heterocycles as α-Glucosidase Inhibitors for the Treatment of Type-2 Diabetes Mellitus
One of the most effective therapeutic decencies in the treatment of Type 2 Diabetes Mellitus
is the inhibition of α-glucosidase enzyme, which is present at the brush border of the …
is the inhibition of α-glucosidase enzyme, which is present at the brush border of the …
Overview of human 20 alpha-hydroxysteroid dehydrogenase (AKR1C1): Functions, regulation, and structural insights of inhibitors
X Chu, S He, Y Liu, Y Liu, F Feng, Q Guo, L Zhao… - Chemico-Biological …, 2022 - Elsevier
Human aldo-keto reductase family 1C1 (AKR1C1) is an important enzyme involved in
human hormone metabolism, which is mainly responsible for the metabolism of …
human hormone metabolism, which is mainly responsible for the metabolism of …
Design, synthesis, antimicrobial evaluation and docking studies of urea-triazole-amide hybrids
Abstract A series of urea-1, 2, 3-triazole-amide hybrids was designed and synthesized via
click reaction of urea derivatives containing a propargyl unit with 2-bromo-N …
click reaction of urea derivatives containing a propargyl unit with 2-bromo-N …
The Natural Sweetener Stevia: An Updated Review on its Phytochemistry, Health Benefits, and Anti-diabetic study
S Patel, A Navale - Current Diabetes Reviews, 2024 - ingentaconnect.com
Stevia rebaudiana Bertoni is one of the significant high qualities of non-caloric sugar
substitute sweetener plants against diabetes disease. Diabetes mellitus is one of the most …
substitute sweetener plants against diabetes disease. Diabetes mellitus is one of the most …
Design, synthesis, molecular dynamic simulation, DFT analysis, computational pharmacology and decoding the antidiabetic molecular mechanism of sulphonamide …
SD Ranade, SG Alegaon, NA Khatib, S Gharge… - Journal of Molecular …, 2024 - Elsevier
In search of novel antidiabetic agents, the study was framed to hybridize and synthesize
molecules based on scaffolds of benzenesulfonamide and thiazolidine-4-one, efficiently …
molecules based on scaffolds of benzenesulfonamide and thiazolidine-4-one, efficiently …
[HTML][HTML] Glycogen synthase kinase 3β inhibition and insulin-receptor binding enhancement of compounds isolated from wild leafy vegetable Acalypha alnifolia
R Ponnusamy, K Giriraj, MS AM, P Thangaraj… - Phytomedicine Plus, 2022 - Elsevier
Background The traditional information of Acalypha alnifolia is captivate towards its
therapeutic efficacy against diabetes along with the scientific confirmation were leads to an …
therapeutic efficacy against diabetes along with the scientific confirmation were leads to an …
Evaluation of in vitro anti-diabetic activity of methanolic extract of Ixora coccinea flowers
L Anila, MS Hashim - Journal of Pharmaceutical Sciences and …, 2019 - search.proquest.com
According to WHO, it is estimated that 3% of the world's population have diabetes and the
prevalence is expected to double by the year 2025 to 6.3%[2]. With a long course and …
prevalence is expected to double by the year 2025 to 6.3%[2]. With a long course and …
Synthesis of Pyrimidinyl Benzazolyl Urea Derivatives as Antimicrobial and Antioxidant Agents
N Hussain Basha, K Narendra Babu… - Polycyclic Aromatic …, 2022 - Taylor & Francis
A library of pyrimidinyl benzazolyl urea derivatives were synthesized from pyrimidine-2-
amine and methyl benzazolylcarbamate in the presence of potassium tert-butoxide in DMF …
amine and methyl benzazolylcarbamate in the presence of potassium tert-butoxide in DMF …
Synthesis, Characterization and Biological Evaluation of Thiazolidinedione Derivative as Novel Antidiabetic Agents
Thiazolidinedione derivative have Antihyperglycemic activity, they are agonists for the
peroxisome proliferator-activated receptor (PPAR), which controls glucose synthesis …
peroxisome proliferator-activated receptor (PPAR), which controls glucose synthesis …