Biginelli reaction: an overview

H Nagarajaiah, A Mukhopadhyay, JN Moorthy - Tetrahedron Letters, 2016 - Elsevier
Biginelli reaction involves acid-catalyzed one-pot synthesis of 3, 4-dihydropyrimidin-2 (1 H)-
ones (DHPMs) using easily-accessible starting materials, namely, aldehyde, active …

Synthesis of 3, 4-dihydropyrimidin (thio) one containing scaffold: Biginelli-like reactions

F Sánchez-Sancho, M Escolano, D Gaviña, AG Csáky… - Pharmaceuticals, 2022 - mdpi.com
The interest in 3, 4-dihydropyrimidine-2 (1 H)-(thio) ones is increasing every day, mainly due
to their paramount biological relevance. The Biginelli reaction is the classical approach to …

Synthesis, characterization, and application of novel aryldiazenyl disperse dyes on polyester fabrics

AZ Omar, AM Khamis, EA Hamed, SK El-Sadany… - Scientific Reports, 2023 - nature.com
Azo dyes are widely used for dyeing polyester fabrics but require optimization of properties
like color strength and fastness. Fourteen novel disperse azo dyes were synthesized from 2 …

Similarity and competition between Biginelli and Hantzsch reactions: An opportunity for modern medicinal chemistry

P Costanzo, M Nardi, M Oliverio - European Journal of Organic …, 2020 - Wiley Online Library
Similarity and competition between multicomponent reactions with similar mechanisms and
leading to similar scaffolds can be a useful tool for medicinal chemistry. In this review, we …

A bio-waste derived sustainable heterogenous catalyst for Biginelli reaction

A Patil, V Chaudhari, SR Patil, GP Borse… - Journal of the Indian …, 2023 - Elsevier
This study is targeted at agricultural waste-derived heterogeneous catalysts, which have
been effectively employed for Biginelli reaction. The application of cotton waste (Gossypium) …

Synthesis of dihydropyrimidinone and dihydropyridine derivatives by a GQDs-based magnetically nanocatalyst under solvent-free conditions

M Najjar, MA Nasseri, M Darroudi… - Journal of Environmental …, 2022 - Elsevier
A novel and heterogeneous catalyst were prepared of magnetic nanoparticles Fe 3 O 4
coated with silicate modified with graphene quantum dot-copper (GQD/Cu) and used as an …

Synthesis, crystal structure and antibacterial studies of dihydropyrimidines and their regioselectively oxidized products

AE Huseynzada, C Jelch, HVN Akhundzada… - RSC …, 2021 - pubs.rsc.org
The syntheses and investigations of new biologically active derivatives of
dihydropyrimidines by Biginelli reaction in the presence of copper triflate are reported. Due …

Trinuclear cis–[MoVIO2] complexes catalyzed efficient synthesis of 3, 4-dihydropyrimidin-2 (1H)-one based biomolecules via one-pot-three-components Biginelli …

MR Maurya, D Singh, R Tomar, P Gupta - Inorganica Chimica Acta, 2022 - Elsevier
The tricompartmental ligands tris (H 2 ONO)[H 6 L 1-3 (I–III)] having C 3 symmetry, obtained
from the condensation of benzene-1, 3, 5-tricarbohydrazide and 3-acetyl-2-hydroxy-6-methyl …

Highly Efficient Synthesis of Substituted 3,4-Dihydropyrimidin-2-(1H)-ones (DHPMs) Catalyzed by Hf(OTf)4: Mechanistic Insights into Reaction Pathways under Metal …

R Kong, SB Han, JY Wei, XC Peng, ZB Xie, SS Gong… - Molecules, 2019 - mdpi.com
In our studies on the catalytic activity of Group IVB transition metal Lewis acids, Hf (OTf) 4
was identified as a highly potent catalyst for” one-pot, three-component” Biginelli reaction …

[HTML][HTML] Molecular structure, frontier molecular orbitals, MESP and UV–visible spectroscopy studies of Ethyl 4-(3, 4-dimethoxyphenyl)-6-methyl-2-oxo-1, 2, 3, 4 …

VA Adole, BS Jagdale, TB Pawar… - Material Science …, 2020 - materialsciencejournal.org
In the current investigation, we wish to report a combined study on the theoretical and
experimental investigation of structural, molecular, and spectral properties of ethyl 4-(3, 4 …