The efficacy of psychotherapies and pharmacotherapies for mental disorders in adults: an umbrella review and meta‐analytic evaluation of recent meta‐analyses

F Leichsenring, C Steinert, S Rabung… - World …, 2022 - Wiley Online Library
Mental disorders represent a worldwide public health concern. Psychotherapies and
pharmacotherapies are recommended as first line treatments. However, evidence has …

Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities

MA Ortega, MA Álvarez-Mon, C García-Montero… - Molecular …, 2023 - nature.com
Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

Increased risk for COVID‐19 breakthrough infection in fully vaccinated patients with substance use disorders in the United States between December 2020 and …

L Wang, QQ Wang, PB Davis, ND Volkow… - World …, 2022 - Wiley Online Library
Individuals with substance use disorders (SUDs) are at increased risk for COVID‐19
infection and for adverse outcomes of the infection. Though vaccines are highly effective …

Efficacy and acceptability of pharmacological, psychosocial, and brain stimulation interventions in children and adolescents with mental disorders: an umbrella review

CU Correll, S Cortese, G Croatto, F Monaco… - World …, 2021 - Wiley Online Library
Top‐tier evidence on the safety/tolerability of 80 medications in children/adolescents with
mental disorders has recently been reviewed in this journal. To guide clinical practice, such …

Comparative efficacy and tolerability of pharmacological interventions for acute bipolar depression in adults: a systematic review and network meta-analysis

A Yildiz, S Siafis, D Mavridis, E Vieta… - The Lancet Psychiatry, 2023 - thelancet.com
Background Bipolar depression constitutes a major public health problem due to its
substantial burden of disease. Although pharmacological interventions are available …

Efficacy and tolerability of combination treatments for major depression: antidepressants plus second-generation antipsychotics vs. esketamine vs. lithium

GH Vázquez, A Bahji, J Undurraga… - Journal of …, 2021 - journals.sagepub.com
Background: Successful treatment of major depressive disorder (MDD) can be challenging,
and failures (" treatment-resistant depression"[TRD]) are frequent. Steps to address TRD …

Efficacy and safety of racemic ketamine and esketamine for depression: a systematic review and meta-analysis

A Bahji, CA Zarate, GH Vazquez - Expert opinion on drug safety, 2022 - Taylor & Francis
Background Racemic ketamine and esketamine have demonstrated rapid antidepressant
effects. We aimed to review the efficacy and safety of racemic and esketamine for …

Real-world effectiveness of pharmacological treatments for bipolar disorder: register-based national cohort study

M Lähteenvuo, T Paljärvi, A Tanskanen… - The British Journal of …, 2023 - cambridge.org
BackgroundPharmacological treatment patterns for bipolar disorder have changed during
recent years, but for better or worse? AimsTo investigate the comparative real-world …

Comparative efficacy and acceptability of psychotherapies for self-harm and suicidal behavior among children and adolescents: a systematic review and network meta …

A Bahji, M Pierce, J Wong, JN Roberge… - JAMA network …, 2021 - jamanetwork.com
Importance Self-harm and suicidal behavior are associated with substantial morbidity and
mortality among children and adolescents. The comparative performance of …

Ketamine for bipolar depression: a systematic review

A Bahji, CA Zarate Jr… - International Journal of …, 2021 - academic.oup.com
Background Ketamine appears to have a therapeutic role in certain mental disorders, most
notably unipolar major depressive disorder. However, its efficacy in bipolar depression is …