Sepsis-induced myocardial dysfunction is increasingly recognized as a major contributor to
outcome of septic shock. Significant strides have been made in understanding the …

Objective: To postulate reasons as to why the benefits seen with novel therapies in animal
models of sepsis fail to translate to the clinical setting. Data Source: MEDLINE searches and …

Introduction: Effective resuscitation with human albumin solutions is achieved with less fluid
than with crystalloid solutions. However, the role of albumin in today's critical care unit is …

Pulmonary hypertension (PH) initially results in compensatory right ventricular (RV)
hypertrophy, but eventually in RV failure. This transition is poorly understood, but may be …

Acute myocardial dysfunction is a typical manifestation of septic shock. Experimentally, the
administration of endotoxin [lipopolysacharride (LPS)] to laboratory animals is frequently …

4. Centers for Disease Control and Prevention. Vital signs: estimated effects of a coordinated
approach for action to reduce antibiotic-resistant infections in health care facilities—United …

IMPLICATIONS: Intravascular volume replacement using human albumin in
hypoalbuminemic elderly cardiac surgery patients aged> 80 yr did not improve inflammatory …

Background Sepsis-induced microcirculatory alterations contribute to tissue hypoxia and
organ dysfunction. In addition to its plasma volume expanding activity, human serum …

Objective: Although nitric oxide (NO) is a known regulator of cardiovascular function, the
effect of NO overproduction during sepsis on capillary oxygen transport and local tissue …

Background Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory
autoimmune disease of the central nervous system. Serum albumin (SA) has antioxidant …