Targeting multiple signaling pathways in cancer: The rutin therapeutic approach
Z Nouri, S Fakhri, K Nouri, CE Wallace, MH Farzaei… - Cancers, 2020 - mdpi.com
Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …
conventional therapies used in cancer prevention/treatment suffer from low efficacy …
Targeting the JAK/STAT signaling pathway using phytocompounds for cancer prevention and therapy
S Bose, S Banerjee, A Mondal, U Chakraborty… - Cells, 2020 - mdpi.com
Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …
Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …
Advances in phytochemical delivery systems for improved anticancer activity
R Lagoa, J Silva, JR Rodrigues, A Bishayee - Biotechnology advances, 2020 - Elsevier
Natural compounds have significant anticancer pharmacological activities, but often suffer
from low bioavailability and selectivity that limit therapeutic use. The present work critically …
from low bioavailability and selectivity that limit therapeutic use. The present work critically …
Tea consumption and disease correlations
Tea is the most widely consumed beverage in the world next to water and is obtained from
the leaves Camellia sinensis. In recent years, the potential health benefits and effect …
the leaves Camellia sinensis. In recent years, the potential health benefits and effect …
Epigallocatechin gallate as a nutraceutical to potentially target the metabolic syndrome: Novel insights into therapeutic effects beyond its antioxidant and anti …
Epigallocatechin gallate (EGCG) is one of the most abundant and powerful flavonoids
contained in green tea. Because of the global increase in green tea consumption, there has …
contained in green tea. Because of the global increase in green tea consumption, there has …
Role of phytonutrients in nutrigenetics and nutrigenomics perspective in curing breast cancer
Breast cancer (BC) is one of the most common type of cancer and an important contributor to
female mortality. Several genes and epigenetic modifications are involved in the …
female mortality. Several genes and epigenetic modifications are involved in the …
Effects of quercetin-loaded nanoparticles on MCF-7 human breast cancer cells
Background and objectives: Previous studies have shown anti-tumor activity of quercetin
(QT). However, the low bioavailability of QT has restricted its use. This study aimed to assess …
(QT). However, the low bioavailability of QT has restricted its use. This study aimed to assess …
Modulation of dysregulated cancer metabolism by plant secondary metabolites: A mechanistic review
Several signaling pathways and basic metabolites are responsible for the control of
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …
Effects and mechanisms of dietary bioactive compounds on breast cancer prevention
Breast cancer (BC) is the most often diagnosed cancer among females globally and has
become an increasing global health issue over the last decades. Despite the substantial …
become an increasing global health issue over the last decades. Despite the substantial …