Over the years, a broad spectrum of applications of the radionuclide holmium-166 as a
medical isotope has been established. The isotope holmium-166 is attractive as it emits high …

One of the most common cancers among men worldwide (Fig. 1) is prostate cancer (PCa). 1
Prostate-specific membrane antigen (PSMA) is a valuable target for the diagnosis of PCa …

Bone pain arising from secondary skeletal malignancy constitutes one of the most common
types of chronic pain among patients with cancer which can lead to rapid deterioration of the …

Developing new bone pain palliation agents is a mandate in handling end-stage cancer
patients around the world. Possibly, Lu-177 ethylenediaminetetramethylene phosphonic …

In this work, the absorbed dose to each organ of human for 166 Ho-TTHMP was evaluated
based on biodistribution studies in rats by a RADAR method and was compared with 166 Ho …

Application of bone-seeking radiopharmaceuticals is one of the modalities in the
management of metastatic bone pain. The present study aimed to investigate the potential of …

Therapeutic radiopharmaceuticals for bone pain palliation play an important role in
providing quality of life for cancer patients with metastatic bone cancer. There is currently …

In this work, the cocktail complex 153 Sm/177 Lu-EDTMP was prepared in high
radiochemical purity (more than 99%) using in house synthesized EDTMP ligand for …

Skeletal uptake of β− emitters of DOTMP complexes is used for the bone pain palliation. In
this study, two moderate energy β− emitters, 177 Lu (T 1/2= 6.7 days, E βmax= 497 keV) and …

Background and Objective: Skeletal uptake of 90Y-1, 4, 7, 10-tetraazacyclododecane-1, 4, 7,
10-tetramethylene-phosphonate (DOTMP) is used to deliver high doses of this …