Adipose tissue derived stem cells (ADSCs) are mesenchymal stem cells identified within
subcutaneous tissue at the base of the hair follicle (dermal papilla cells), in the dermal …

Growth differentiation factor (GDF11) is a member of TGF-β/BMP superfamily that activates
Smad and non-Smad signaling pathways and regulates expression of its target nuclear …

Brown adipose tissue (BAT) activity contributes to cardiovascular health by its energy-
dissipating capacity but how BAT modulates vascular function and atherosclerosis through …

Whether bone marrow modulates systemic metabolism remains unknown. Our recent study
suggested that myeloid-derived growth factor (MYDGF) improves insulin resistance. Here …

Aging is the biggest risk factor for several neurodegenerative diseases. Parabiosis
experiments have established that old mouse brains are improved by exposure to young …

Whether bone marrow modulates systemic metabolism remains unknown. Here, we found
that (i) myeloid cell–specific myeloid-derived growth factor (MYDGF) deficiency exacerbated …

Age-related impairment of neurovascular coupling (NVC;“functional hyperemia”) is a critical
factor in the development of vascular cognitive impairment (VCI). Recent geroscience …

ABSTRACT Growth differentiation factor 11 (GDF11) is a member of the transforming growth
factor-β superfamily that has garnered significant attention due to its anti-cardiac aging …

Adipose-Derived Stem Cells (ADSC) are present within the hypodermis and are also
expected to play a pivotal role in wound healing, immunomodulation, and rejuvenation …

Aims/hypothesis Myeloid-derived growth factor (MYDGF), mainly secreted by bone marrow-
derived cells, has been known to promote glucagon-like peptide-1 production and improve …