[HTML][HTML] Virus-like particles: Revolutionary platforms for developing vaccines against emerging infectious diseases

H Tariq, S Batool, S Asif, M Ali, BH Abbasi - Frontiers in microbiology, 2022 - frontiersin.org
Virus-like particles (VLPs) are nanostructures that possess diverse applications in
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …

[HTML][HTML] Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

[HTML][HTML] Platforms for production of protein-based vaccines: from classical to next-generation strategies

R Cid, J Bolívar - Biomolecules, 2021 - mdpi.com
To date, vaccination has become one of the most effective strategies to control and reduce
infectious diseases, preventing millions of deaths worldwide. The earliest vaccines were …

[HTML][HTML] Platforms, advances, and technical challenges in virus-like particles-based vaccines

R Gupta, K Arora, SS Roy, A Joseph… - Frontiers in …, 2023 - frontiersin.org
Viral infectious diseases threaten human health and global stability. Several vaccine
platforms, such as DNA, mRNA, recombinant viral vectors, and virus-like particle-based …

Virus‐like particles as powerful vaccination strategy against human viruses

I Hadj Hassine, M Ben M'hadheb… - Reviews in Medical …, 2024 - Wiley Online Library
Nowadays, viruses are not only seen as causative agents of viral infectious diseases but
also as valuable research materials for various biomedical purposes, including recombinant …

Virus-like particles: the new frontier of vaccines for animal viral infections

E Crisci, J Bárcena, M Montoya - Veterinary immunology and …, 2012 - Elsevier
Vaccination continues to be the main approach to protect animals from infectious diseases.
Until recently, all licensed vaccines were developed using conventional technologies …

[HTML][HTML] Molecular exclusion limits for diffusion across a porous capsid

E Selivanovitch, B LaFrance, T Douglas - Nature communications, 2021 - nature.com
Molecular communication across physical barriers requires pores to connect the
environments on either side and discriminate between the diffusants. Here we use porous …

Next generation vaccines and vectors: Designing downstream processes for recombinant protein‐based virus‐like particles

CL Effio, J Hubbuch - Biotechnology journal, 2015 - Wiley Online Library
In recent years, the development of novel recombinant virus‐like particles (VLPs) has been
generating new perspectives for the prevention of untreated and arising infectious diseases …

Insect cells as a production platform of complex virus-like particles

F Fernandes, AP Teixeira, N Carinhas… - Expert review of …, 2013 - Taylor & Francis
Virus-like particles (VLPs) are multiprotein structures that resemble the conformation of
native viruses but lack a viral genome, potentiating their application as safer and cheaper …

[HTML][HTML] The breadth of bacteriophages contributing to the development of the phage-based vaccines for COVID-19: An ideal platform to design the multiplex vaccine

I Ul Haq, K Krukiewicz, G Yahya, MU Haq… - International Journal of …, 2023 - mdpi.com
Phages are highly ubiquitous biological agents, which means they are ideal tools for
molecular biology and recombinant DNA technology. The development of a phage display …