The molecular basis of drug addiction: linking epigenetic to synaptic and circuit mechanisms

EJ Nestler, C Lüscher - Neuron, 2019 - cell.com
Addiction is a disease in which, after a period of recreational use, a subset of individuals
develops compulsive use that does not stop even in light of major negative consequences …

Human genetic variation and its contribution to complex traits

KA Frazer, SS Murray, NJ Schork, EJ Topol - Nature Reviews Genetics, 2009 - nature.com
The last few years have seen extensive efforts to catalogue human genetic variation and
correlate it with phenotypic differences. Most common SNPs have now been assessed in …

Subspecific origin and haplotype diversity in the laboratory mouse

H Yang, JR Wang, JP Didion, RJ Buus, TA Bell… - Nature …, 2011 - nature.com
Here we provide a genome-wide, high-resolution map of the phylogenetic origin of the
genome of most extant laboratory mouse inbred strains. Our analysis is based on the …

The mouse ascending: perspectives for human-disease models

N Rosenthal, S Brown - Nature cell biology, 2007 - nature.com
The laboratory mouse is widely considered the model organism of choice for studying the
diseases of humans, with whom they share 99% of their genes. A distinguished history of …

A sequence-based variation map of 8.27 million SNPs in inbred mouse strains

KA Frazer, E Eskin, HM Kang, MA Bogue, DA Hinds… - Nature, 2007 - nature.com
A dense map of genetic variation in the laboratory mouse genome will provide insights into
the evolutionary history of the species and lead to an improved understanding of the …

Lipid imaging by mass spectrometry–a review

D Gode, DA Volmer - Analyst, 2013 - pubs.rsc.org
Mass spectrometry imaging (MSI) has proven to be extremely useful for applications such as
the spatial analysis of peptides and proteins in biological tissue, the performance …

Mouse models for infectious diseases caused by Staphylococcus aureus

HK Kim, D Missiakas, O Schneewind - Journal of immunological methods, 2014 - Elsevier
Staphylococcus aureus–a commensal of the human skin, nares and gastrointestinal tract–is
also a leading cause of bacterial skin and soft tissue infection (SSTIs), bacteremia, sepsis …

On the subspecific origin of the laboratory mouse

H Yang, TA Bell, GA Churchill… - Nature …, 2007 - nature.com
The genome of the laboratory mouse is thought to be a mosaic of regions with distinct
subspecific origins. We have developed a high-resolution map of the origin of the laboratory …

The genetic landscape of type 2 diabetes in mice

SM Clee, AD Attie - Endocrine reviews, 2007 - academic.oup.com
Inbred mouse strains provide genetic diversity comparable to that of the human population.
Like humans, mice have a wide range of diabetes-related phenotypes. The inbred mouse …

Detecting DNA and RNA and differentiating single-nucleotide variations via field-effect transistors

KM Cheung, JM Abendroth, N Nakatsuka, B Zhu… - Nano …, 2020 - ACS Publications
We detect short oligonucleotides and distinguish between sequences that differ by a single
base, using label-free, electronic field-effect transistors (FETs). Our sensing platform utilizes …