The circadian timing system governs daily biological rhythms, synchronising physiology and
behaviour to the temporal world. External time cues, including the light‐dark cycle and …

Despite considerable advances in the past few years, obesity and type 2 diabetes mellitus
(T2DM) remain two major challenges for public health systems globally. In the past 9 years …

Light exerts a wide range of effects on mammalian physiology and behavior. As well as
synchronizing circadian rhythms to the external environment, light has been shown to …

The circadian system is responsible for internal functions and regulation of the organism
according to environmental cues (zeitgebers). Circadian rhythm dysregulation or …

Circadian rhythms are 24-h patterns regulating behavior, organs, and cells in living
organisms. These rhythms align biological functions with regular and predictable …

Night work increases diabetes risk. Misalignment between the central circadian “clock” and
daily behaviors, typical in night workers, impairs glucose tolerance, likely due to internal …

REV-ERB nuclear receptors are potent transcriptional repressors that play an important role
in the core mammalian molecular clock and metabolism. Deletion of both REV-ERBα and its …

For many years, a connection between circadian clocks and cancer has been postulated.
Here we describe an unexpected function for the circadian repressor CRY2 as a component …

Most organisms use internal biological clocks to match behavioural and physiological
processes to specific phases of the day–night cycle. Central to this is the synchronisation of …

Proanthocyanidins (PAs) are the most abundant flavonoids in the human diet. Several
epidemiological studies connect PA consumption and health benefits and the designation of …