[HTML][HTML] Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer's disease

A Jullienne, JI Szu, R Quan, MV Trinh… - Frontiers in Aging …, 2023 - ncbi.nlm.nih.gov
Methods Male and female 5xFAD and wild type (WT) littermates underwent in vivo 18 F-
fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging at 4, 6, and 12 …

[HTML][HTML] Mapping acute neuroinflammation in vivo with diffusion-MRI in rats given a systemic lipopolysaccharide challenge

E Kim, IC Figueiredo, C Simmons, K Randall… - Brain, Behavior, and …, 2023 - Elsevier
It is becoming increasingly apparent that neuroinflammation plays a critical role in an array
of neurological and psychiatric disorders. Recent studies have demonstrated the potential of …

[HTML][HTML] versaFlow: a versatile pipeline for resolution adapted diffusion MRI processing and its application to studying the variability of the PRIME-DE database

A Valcourt Caron, A Shmuel, Z Hao… - Frontiers in …, 2023 - frontiersin.org
The lack of “gold standards” in Diffusion Weighted Imaging (DWI) makes validation
cumbersome. To tackle this task, studies use translational analysis where results in humans …

[HTML][HTML] versaFlow: a versatile pipeline for resolution adapted diffusion MRI processing and its application to studying the variability of the PRIME-DE database

AV Caron, A Shmuel, Z Hao… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
The lack of “gold standards” in Diffusion Weighted Imaging (DWI) makes validation
cumbersome. To tackle this task, studies use translational analysis where results in humans …

Quantitative diffusion imaging and genotype‐by‐sex interactions in a rat model of Alexander disease

NA Stowe, AP Singh, BR Barnett, SY Yi… - Magnetic …, 2024 - Wiley Online Library
Purpose The clinical diagnosis and classification of Alexander disease (AxD) relies in part
on qualitative neuroimaging biomarkers; however, these biomarkers fail to distinguish and …

[HTML][HTML] Differentiation of white matter histopathology using b-tensor encoding and machine learning

R Rios-Carrillo, A Ramírez-Manzanares… - Plos one, 2023 - journals.plos.org
Diffusion-weighted magnetic resonance imaging (DW-MRI) is a non-invasive technique that
is sensitive to microstructural geometry in neural tissue and is useful for the detection of …

Non-invasive MRI of Blood-Cerebrospinal Fluid-Barrier Function: a Functional Biomarker of Early Alzheimer's Disease Pathology

C Perera, R Cruz, N Shemesh, T Carvalho, DL Thomas… - bioRxiv, 2024 - biorxiv.org
INTRODUCTION Choroid plexus (CP) dysfunction is thought to contribute to toxic protein
build-up in neurodegenerative disorders, including Alzheimer's disease (AD). However, the …