Tumor microenvironment in gastric cancers

Y Oya, Y Hayakawa, K Koike - Cancer science, 2020 - Wiley Online Library
The tumor microenvironment favors the growth and expansion of cancer cells. Many cell
types are involved in the tumor microenvironment such as inflammatory cells, fibroblasts …

Molecular mechanisms of the preventable causes of cancer in the United States

EA Golemis, P Scheet, TN Beck… - Genes & …, 2018 - genesdev.cshlp.org
Abstract Annually, there are 1.6 million new cases of cancer and nearly 600,000 cancer
deaths in the United States alone. The public health burden associated with these numbers …

Anticancer and anti-inflammatory properties of mangiferin: A review of its molecular mechanisms

S Mei, H Ma, X Chen - Food and Chemical Toxicology, 2021 - Elsevier
Chronic inflammation is crucial for the pathological process of tumors due to increasing the
infiltration of cytokines, growth factors, and chemokines to the tumor microenvironment …

The Gum–Gut axis: periodontitis and the risk of gastrointestinal cancers

G Baima, DG Ribaldone, F Romano, M Aimetti… - Cancers, 2023 - mdpi.com
Simple Summary Periodontitis, a chronic inflammatory disease of the gums, and the oral
microbiome have been recently implicated in the development of various cancers. Due to …

Cancer stem cells and the tumor microenvironment in gastric cancer

Y Yang, WJ Meng, ZQ Wang - Frontiers in Oncology, 2022 - frontiersin.org
Gastric cancer (GC) remains one of the leading causes of cancer-related death worldwide.
Cancer stem cells (CSCs) might be responsible for tumor initiation, relapse, metastasis and …

Autoimmunity and gastric cancer

N Bizzaro, A Antico, D Villalta - International Journal of Molecular …, 2018 - mdpi.com
Alterations in the immune response of patients with autoimmune diseases may predispose
to malignancies, and a link between chronic autoimmune gastritis and gastric cancer has …

Digesting the role of JAK-STAT and cytokine signaling in oral and gastric cancers

Y Ni, JT Low, J Silke, LA O'Reilly - Frontiers in Immunology, 2022 - frontiersin.org
When small proteins such as cytokines bind to their associated receptors on the plasma
membrane, they can activate multiple internal signaling cascades allowing information from …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

The immunopathogenesis of Helicobacter pylori-induced gastric cancer: a narrative review

M Shirani, S Shariati, M Bazdar… - Frontiers in …, 2024 - frontiersin.org
Helicobacter pylori infection is a well-established risk factor for the development of gastric
cancer (GC). Understanding the immunopathogenesis underlying this association is crucial …

Anti-inflammatory effects of gingerol on lipopolysaccharide-stimulated RAW 264.7 cells by inhibiting NF-κB signaling pathway

N Liang, Y Sang, W Liu, W Yu, X Wang - Inflammation, 2018 - Springer
Gingerol was the main functional substance of Zingiberaceous plant which has been known
as traditional medicine for thousands of years. The purpose of this experiment was to …