Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

With the rapid development of nanotechnology, engineered nanomaterials (ENMs) are
widely used in various fields. This has exacerbated the environmental pollution and human …

Asthma exacerbations caused by respiratory viral infections are a serious global health
problem. Impaired antiviral immunity is thought to contribute to the pathogenesis, but the …

Mitochondria are versatile organelles and essential components of numerous biological
processes such as energy metabolism, signal transduction, and cell fate determination. In …

Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung injury
characterized by diffuse alveolar damage. The period prevalence of ARDS was 10.4% of …

The mitochondrial integrity and function in endothelial cells are essential for angiogenesis.
TIMM44 (translocase of inner mitochondrial membrane 44) is essential for integrity and …

Cembranolides are characteristic metabolites in marine soft corals, with complex structures
and widespread biological activities. However, seldom has an intensive pharmacological …

Idiopathic pulmonary fibrosis (IPF) is a lung disease that worsens over time, causing fibrosis
in the lungs and ultimately resulting in respiratory failure and a high risk of death …

Idiopathic pulmonary fibrosis (IPF) is a progressive fatal lung disease with a limited
therapeutic strategy. Mitochondrial oxidative stress in macrophages is directly linked to IPF …

Acute lung injury (ALI) is generally caused by severe respiratory infection and characterized
by overexuberant inflammatory responses and inefficient pathogens-containing, the two …