Glycoconjugates: synthesis, functional studies, and therapeutic developments
Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …
Aptamer-based biosensors for virus protein detection
B Lou, Y Liu, M Shi, J Chen, K Li, Y Tan, L Chen… - TrAC Trends in …, 2022 - Elsevier
Virus threatens life health seriously. The accurate early diagnosis of the virus is vital for
clinical control and treatment of virus infection. Aptamers are small single-stranded …
clinical control and treatment of virus infection. Aptamers are small single-stranded …
Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS)
coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic …
coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic …
StrucGP: de novo structural sequencing of site-specific N-glycan on glycoproteins using a modularization strategy
J Shen, L Jia, L Dang, Y Su, J Zhang, Y Xu, B Zhu… - Nature …, 2021 - nature.com
Precision mapping of glycans at structural and site-specific level is still one of the most
challenging tasks in the glycobiology field. Here, we describe a modularization strategy for …
challenging tasks in the glycobiology field. Here, we describe a modularization strategy for …
Global aspects of viral glycosylation
I Bagdonaite, HH Wandall - Glycobiology, 2018 - academic.oup.com
Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …
infections of different severity, ranging from no or very few symptoms to lethal disease as …
An overview of influenza A virus genes, protein functions, and replication cycle highlighting important updates
RP Chauhan, ML Gordon - Virus Genes, 2022 - Springer
The recent research findings on influenza A virus (IAV) genome biology prompted us to
present a comprehensive overview of IAV genes, protein functions, and replication cycle …
present a comprehensive overview of IAV genes, protein functions, and replication cycle …
Generation of a live attenuated influenza A vaccine by proteolysis targeting
The usefulness of live attenuated virus vaccines has been limited by suboptimal
immunogenicity, safety concerns or cumbersome manufacturing processes and techniques …
immunogenicity, safety concerns or cumbersome manufacturing processes and techniques …
[HTML][HTML] A carbohydrate-binding protein from the edible lablab beans effectively blocks the infections of influenza viruses and SARS-CoV-2
YM Liu, M Shahed-Al-Mahmud, X Chen, TH Chen… - Cell reports, 2020 - cell.com
The influenza virus hemagglutinin (HA) and coronavirus spike (S) protein mediate virus
entry. HA and S proteins are heavily glycosylated, making them potential targets for …
entry. HA and S proteins are heavily glycosylated, making them potential targets for …
Within-host diversity of SARS-CoV-2 in COVID-19 patients with variable disease severities
HA Al Khatib, FM Benslimane, IE Elbashir… - Frontiers in cellular …, 2020 - frontiersin.org
Background: The ongoing pandemic of SARS-COV-2 has already infected more than eight
million people worldwide. The majority of COVID-19 patients either are asymptomatic or …
million people worldwide. The majority of COVID-19 patients either are asymptomatic or …
Influenza vaccine effectiveness: defining the H3N2 problem
EA Belongia, HQ McLean - Clinical Infectious Diseases, 2019 - academic.oup.com
Observational studies have consistently shown that influenza vaccine effectiveness (VE) is
lower for H3N2 relative to H1N1pdm09 and type B, and this is not entirely explained by …
lower for H3N2 relative to H1N1pdm09 and type B, and this is not entirely explained by …