[HTML][HTML] Update on the diagnosis of tuberculosis

I Kontsevaya, AM Cabibbe, DM Cirillo… - Clinical Microbiology …, 2023 - Elsevier
Background Tuberculosis remains a global public health threat, and the development of
rapid and precise diagnostic tools is the key to enabling the early start of treatment …

Initial immune response after exposure to Mycobacterium tuberculosis or to SARS-COV-2: similarities and differences

A Aiello, S Najafi-Fard, D Goletti - Frontiers in Immunology, 2023 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …

Research tests for the diagnosis of tuberculosis infection

T Alonzi, F Repele, D Goletti - Expert Review of Molecular …, 2023 - Taylor & Francis
Introduction Despite huge efforts, tuberculosis (TB) is still a major public health threat
worldwide, it is estimated that a quarter of the global population is infected by …

Role of B cells in Mycobacterium tuberculosis infection

P Stewart, S Patel, A Comer, S Muneer, U Nawaz… - Vaccines, 2023 - mdpi.com
Historically, research on the immunologic response to Mycobacterium tuberculosis (M. tb)
infection has focused on T cells and macrophages, as their role in granuloma formation has …

Host biomarker-based quantitative rapid tests for detection and treatment monitoring of tuberculosis and COVID-19

L Pierneef, A van Hooij, D de Jong, EMTK Fat… - Iscience, 2023 - cell.com
Diagnostic services for tuberculosis (TB) are not sufficiently accessible in low-resource
settings, where most cases occur, which was aggravated by the COVID-19 pandemic. Early …

Mouse Models for Mycobacterium tuberculosis Pathogenesis: Show and Do Not Tell

P Soldevilla, C Vilaplana, PJ Cardona - Pathogens, 2022 - mdpi.com
Science has been taking profit from animal models since the first translational experiments
back in ancient Greece. From there, and across all history, several remarkable findings have …

Primary Tuberculosis of Buccal and Labial Mucosa: Literature Review and a Rare Case Report of a Public Health Menace

S Sriram, S Hasan, S Saeed, SA Ahmad… - Case Reports in …, 2023 - Wiley Online Library
Tuberculosis (TB) is a chronic granulomatous infectious disorder, caused by Mycobacterium
tuberculosis. Despite the recent advancements in antitubercular therapy (ATT), it remains a …

Discovery of novel transketolase epitopes and the development of IgG-based tuberculosis serodiagnostics

J Talreja, C Peng, TM Nguyen, S Draghici… - Microbiology …, 2023 - Am Soc Microbiol
Despite advances in rapid molecular techniques for tuberculosis (TB) diagnostics, there is
an unmet need for a point-of-care, nonsputum-based test. Previously, through a T7 phage …

Integrating pathogen-and host-derived blood biomarkers for enhanced tuberculosis diagnosis: a comprehensive review

Z Li, Y Hu, W Wang, F Zou, J Yang, W Gao… - Frontiers in …, 2024 - frontiersin.org
This review explores the evolving landscape of blood biomarkers in the diagnosis of
tuberculosis (TB), focusing on biomarkers derived both from the pathogen and the host …

Antibodies as clinical tools for tuberculosis

S McIntyre, J Warner, C Rush… - Frontiers in …, 2023 - frontiersin.org
Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide. Global research
efforts to improve TB control are hindered by insufficient understanding of the role that …