Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis

P Allawadhi, V Singh, K Govindaraj, I Khurana… - Carbohydrate …, 2022 - Elsevier
Polysaccharides are biopolymers distinguished by their complex secondary structures
executing various roles in microorganisms, plants, and animals. They are made up of long …

Chitosan oligosaccharide/alginate nanoparticles as an effective carrier for astaxanthin with improving stability, in vitro oral bioaccessibility, and bioavailability

FN Sorasitthiyanukarn, C Muangnoi, P Rojsitthisak… - Food …, 2022 - Elsevier
Astaxanthin (ATX), a hydrophobic xanthophyll family of carotenoids, has various
advantageous biological activities. Its use as a bioactive compound in functional foods …

Surface-modified bilosomes nanogel bearing a natural plant alkaloid for safe management of rheumatoid arthritis inflammation

MH Elkomy, NK Alruwaili, M Elmowafy, K Shalaby… - Pharmaceutics, 2022 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory illness affecting the joints. The
characteristic of RA is gradual joint deterioration. Current RA treatment alleviates signs such …

Thymol encapsulated chitosan-Aloe vera films for antimicrobial infection

K Sharma, M Munjal, RK Sharma, M Sharma - International Journal of …, 2023 - Elsevier
Wound healing is an extremely intricate process involving various potential factors that can
contribute towards delayed healing, one of them being bacterial colonization. The current …

Formulation of nanospanlastics as a promising approach for‎ improving the topical delivery of a natural leukotriene inhibitor (3-‎ acetyl-11-keto-β-boswellic acid) …

F Badria, E Mazyed - Drug design, development and therapy, 2020 - Taylor & Francis
Purpose The current study aimed to discuss the potential of nanospanlastics as a surfactant-
based vesicular system for improving the topical delivery of 3-acetyl-11-keto-β-boswellic …

Dextran-b-poly (lactide-co-glycolide) polymersome for oral delivery of insulin: In vitro and in vivo evaluation

M Alibolandi, F Alabdollah, F Sadeghi… - Journal of Controlled …, 2016 - Elsevier
Insulin is the first line therapy in type 1 diabetes and usually patients suffer from three or
more daily insulin injections. It is obvious that patient compliance can be improved greatly if …

Dermatokinetic assessment of luliconazole-loaded nanostructured lipid carriers (NLCs) for topical delivery: QbD-driven design, optimization, and in vitro and ex vivo …

A Mahmood, VK Rapalli, S Gorantla, T Waghule… - Drug Delivery and …, 2022 - Springer
The present study is concerned with the QbD-based design and development of
luliconazole-loaded nanostructured lipid carriers (NLCs) hydrogel for enhanced skin …

Hyaluronic acid-enriched bilosomes: an approach to enhance ocular delivery of agomelatine via D-optimal design: formulation, in vitro characterization, and in vivo …

AA Nemr, GM El-Mahrouk, HA Badie - Drug delivery, 2022 - Taylor & Francis
Agomelatine (AGO) is a dual-functional drug. It uses as an antidepressant when orally
administrated and antiglaucomic when topically applied to the eye. This study aimed to …

Formulation and optimization of nanospanlastics for improving the bioavailability of green tea epigallocatechin gallate

EA Mazyed, DA Helal, MM Elkhoudary… - Pharmaceuticals, 2021 - mdpi.com
The present study aimed to investigate the potential of nanospanlastics for boosting the
bioavailability of epigallocatechin gallate (EGCG). EGCG has valuable effects like anti …

Nano-transfersomal ciprofloxacin loaded vesicles for non-invasive trans-tympanic ototopical delivery: in-vitro optimization, ex-vivo permeation studies, and in-vivo …

AM Al-Mahallawi, OM Khowessah… - International journal of …, 2014 - Elsevier
Ciprofloxacin is a synthetic fluoroquinolone antibiotic that has been used for systemic
treatment of otitis media in adults. It was approved for topical treatment of otorrhea in …