Zebrafish (Danio rerio) is an excellent model to study a wide diversity of human cancers. In
this review, we provide an overview of the genetic and reverse genetic toolbox allowing the …

Zebrafish is an established model for the study of vertebrate development, and is especially
amenable for investigating hematopoiesis, where there is strong conservation of key …

Zebrafish are rapidly becoming a leading model organism for cancer research. The genetic
pathways driving cancer are highly conserved between zebrafish and humans, and the …

t (1; 19)(q23; p13) is one of the most common translocation genes in childhood acute
lymphoblastic leukemia (ALL) and is also present in acute myeloid leukemia (AML) and …

Over the past 15 years, zebrafish have emerged as a powerful tool for studying human
cancers. Transgenic techniques have been employed to model different types of tumors …

The zebrafish animal model is gaining increasing popularity as a tool for studying human
disease. Over the past 15 years, many models of leukemia and other hematological …

Zebrafish offer a powerful vertebrate model for studies of development and disease. The
major advantages of this model include the possibilities of conducting reverse and forward …

Hematopoiesis results in the correct formation of all the different blood cell types. In
mammals, it starts from specific hematopoietic stem and precursor cells residing in the bone …

Simple Summary Discovering new strategies for cancer treatment is critical, considering that
each year millions of deaths are caused by this disease. In this sense, therapies based on …

Zebrafish (Danio rerio) has proven to be a versatile and reliable in vivo experimental model
to study human hematopoiesis and hematological malignancies. As vertebrates, zebrafish …