Background The global burden of invasive fungal infections (IFIs) has shown an upsurge in
recent years due to the higher load of immunocompromised patients suffering from various …

Candidemia and invasive candidiasis are major causes of morbidity and mortality, and their
incidence is increasing because of the growing complexity of patients. Five species of …

Chronic liver disease with cirrhosis is the 12th leading cause of death in the United States,
and alcoholic liver disease accounts for approximately half of all cirrhosis deaths. Chronic …

Every year, Candida, Aspergillus, Cryptococcus and Pneumocystis infect an estimated two
million individuals worldwide. Most are immunocompromised or critically ill. Candida is the …

Background & Aims Alcohol-associated liver disease is a leading indication for liver
transplantation and a leading cause of mortality. Alterations to the gut microbiota contribute …

The paucity of blood granulocyte populations such as neutrophils in laboratory mice is a
notable difference between this model organism and humans, but the cause of this species …

Febrile neutropenia remains an important complication of treatment with cytotoxic
chemotherapy. It is often the first and sometimes the only sign or symptom of infection in this …

β-glucans are a diverse group of polysaccharides composed of β-1, 3 or β-(1, 3-1, 4) linked
glucose monomers. They are mainly synthesized by fungi, plants, seaweed and bacteria …

Fungal infections are a rising threat to our immunocompromised patient population, as well
as other nonimmunocompromised patients with various medical conditions. However, little …

To assess the diagnostic accuracy of 1, 3-β-d-glucan (BDG) assay for diagnosing invasive
fungal infections (IFI), we searched the Medline and Embase databases, and studies …