Exosome processing and characterization approaches for research and technology development
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
Mesenchymal stem cell-derived exosomes: applications in regenerative medicine
Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …
are then released into the extracellular space through a merging of the multivesicular body …
A compendium of single extracellular vesicle flow cytometry
JA Welsh, GJA Arkesteijn, M Bremer… - Journal of …, 2023 - Wiley Online Library
Flow cytometry (FCM) offers a multiparametric technology capable of characterizing single
extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells …
extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells …
Extracellular vesicles: a rising star for therapeutics and drug delivery
S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …
Isolation and characterization of extracellular vesicles and future directions in diagnosis and therapy
KP De Sousa, I Rossi, M Abdullahi… - Wiley …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are a unique and heterogeneous class of lipid bilayer
nanoparticles secreted by most cells. EVs are regarded as important mediators of …
nanoparticles secreted by most cells. EVs are regarded as important mediators of …
Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications
Small extracellular vesicles (sEVs) from mesenchymal stromal/stem cells (MSCs) are
transiting rapidly towards clinical applications. However, discrepancies and controversies …
transiting rapidly towards clinical applications. However, discrepancies and controversies …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more
than 44 million people worldwide. Despite the high disease burden, there is no effective …
than 44 million people worldwide. Despite the high disease burden, there is no effective …
Mesenchymal stem cells-derived exosomes for drug delivery
Y Sun, G Liu, K Zhang, Q Cao, T Liu, J Li - Stem cell research & therapy, 2021 - Springer
Exosomes are extracellular vesicles secreted by various cells, mainly composed of lipid
bilayers without organelles. In recent years, an increasing number of researchers have …
bilayers without organelles. In recent years, an increasing number of researchers have …
Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles
Mesenchymal stromal/stem cells (MSCs) have been widely tested against many diseases,
with more than 1000 registered clinical trials worldwide. Despite many setbacks, MSCs have …
with more than 1000 registered clinical trials worldwide. Despite many setbacks, MSCs have …
Current status and outlook of advances in exosome isolation
W Liu, Z Ma, X Kang - Analytical and Bioanalytical Chemistry, 2022 - Springer
Exosomes are extracellular vesicles with a diameter ranging from 30 to 150 nm, which are
an important medium for intercellular communication and are closely related to the …
an important medium for intercellular communication and are closely related to the …