Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Metals are essential for life, and they play a central role in the struggle between infecting
microbes and their hosts. In fact, an important aspect of microbial pathogenesis is the …

Metabolism is integral to the pathogenicity of Candida albicans, a major fungal pathogen of
humans. As well as providing the platform for nutrient assimilation and growth in diverse …

Hepcidin is the master regulator of iron homeostasis in vertebrates. The synthesis of
hepcidin is induced by systemic iron levels and by inflammatory stimuli. While the role of …

Metals such as Fe, Cu, Zn, and Mn are essential trace nutrients for all kingdoms of life,
including microbial pathogens and their hosts. During infection, the mammalian host …

The opportunistic fungal pathogen Candida albicans acquires essential metals from the
host, yet the host can sequester these micronutrients through a process known as nutritional …

Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …

To colonise their host, pathogens must counter local environmental and immunological
challenges. Here, we reveal that the fungal pathogen Candida albicans exploits diverse host …

Copper is both an essential nutrient and potentially toxic metal, and during infection the host
can exploit Cu in the control of pathogen growth. Here we describe a clever adaptation to Cu …