Sirtuins are the class III of histone deacetylases whose deacetylate of histones is dependent
on nicotinamide adenine dinucleotide (NAD+). Among seven sirtuins, SIRT1 plays a critical …

Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

Inflammation is the most common feature of many chronic diseases and complications, while
playing critical roles in carcinogenesis. Several studies have demonstrated that Nrf2 …

Highlights•Flavonoids from fruits, vegetables, nuts, and legumes inhibit gut
inflammation.•Gut microbiota and host tissue extensively metabolize dietary …

Background: The importance of polyphenols in human health is well known; these
compounds are common in foods, such as fruits, vegetables, spices, extra virgin olive oil and …

The incidence of inflammatory bowel disease (IBD) is rapidly rising throughout the world.
Although tremendous efforts have been made, limited therapeutics are available for IBD …

Inflammatory bowel disease (IBD) is a long-term, progressive, and recurrent intestinal
inflammatory disorder. The pathogenic mechanisms of IBD are multifaceted and associated …

Oxidative stress (OS) is considered as one of the etiologic factors involved in several signals
and symptoms of inflammatory bowel diseases (IBD) that include diarrhea, toxic megacolon …

Inflammatory bowel disease (IBD) is a chronic disorder associated with the inflammation in
the digestive tract. The exact cause of IBD is unknown; nevertheless, in IBD, the …

Resveratrol and other natural stilbenoids, including piceatannol, pterostilbene, and gnetol,
are well-known anti-inflammatory compounds with indisputable activity in vitro as well as in …