The transdermal route of drugs has received increased attention in recent years due to
numerous advantages over the oral and injectable routes, such as avoidance of the hepatic …

The assessment of percutaneous permeation of molecules is a key step in the evaluation of
dermal or transdermal delivery systems. If the drugs are intended for delivery to humans, the …

In the present study, in vitro permeation experiments in a Franz diffusion cell were performed
using different synthetic polymeric membranes and pig ear skin to evaluate a rivastigmine …

In vitro–in vivo correlation (IVIVC) is a predictive mathematical model describing the
relationship between an in vitro property and a relevant in vivo response of drug products …

Introduction: Exposure to heat can impact the clinical efficacy and/or safety of transdermal
and topical drug products. Understanding these heat effects and designing meaningful in …

The pharmacokinetic approach has accelerated the development of high-quality generic
medicines with extraordinary cost savings, transforming the pharmaceutical industry and …

Allergen-specific responses in atopic dermatitis (AD) are skewed toward a Th2 profile.
However, individuals with AD have been shown to make effective virus-specific Th1 …

Purpose The quality testing and approval procedure for most pharmaceutical products is a
streamlined process with standardized procedures for the determination of critical quality …

Diabetic foot ulcer (DFU) is a major debilitating complication of diabetes. Many research
investigations have been conducted with the aims to uncover the diabetic wound healing …

Purpose In vitro skin permeation studies have been used extensively in the development
and optimisation of delivery of actives in vivo. However, there are few reported correlations …