Mechanisms and disease consequences of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …
Carcinogenesis: Failure of resolution of inflammation?
A Fishbein, BD Hammock, CN Serhan… - Pharmacology & …, 2021 - Elsevier
Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …
key characteristic of carcinogens. However, the failure of resolution of inflammation in …
Bioactive lipids, inflammation and chronic diseases
A Leuti, D Fazio, M Fava, A Piccoli, S Oddi… - Advanced Drug Delivery …, 2020 - Elsevier
Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …
cellular and molecular processes involved in health and disease, of which inflammation …
Soluble epoxide hydrolase: a potential target for metabolic diseases: 可溶性表氧化物酶: 代谢性疾病的潜在治疗靶点
摘要环氧‐二十碳三烯酸(Epoxyeicosatrienoic acids, EET) 是花生四烯酸的重要代谢产物. EET
在包括动脉粥样硬化, 高血压, 心脏纤维化, 糖尿病, 非酒精性脂肪肝以及肾脏疾病在内的诸多 …
在包括动脉粥样硬化, 高血压, 心脏纤维化, 糖尿病, 非酒精性脂肪肝以及肾脏疾病在内的诸多 …
Targeting autophagy in obesity: from pathophysiology to management
Obesity poses a severe threat to human health, including the increased prevalence of
hypertension, insulin resistance, diabetes mellitus, cancer, inflammation, sleep apnoea and …
hypertension, insulin resistance, diabetes mellitus, cancer, inflammation, sleep apnoea and …
[HTML][HTML] Eicosanoids: the overlooked storm in coronavirus disease 2019 (COVID-19)?
BD Hammock, W Wang, MM Gilligan… - The American journal of …, 2020 - Elsevier
Severe coronavirus disease 2019 (COVID-19) symptoms, including systemic inflammatory
response and multisystem organ failure, are now affecting thousands of infected patients …
response and multisystem organ failure, are now affecting thousands of infected patients …
Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: a review of recent studies
K Hildreth, SD Kodani, BD Hammock, L Zhao - The Journal of nutritional …, 2020 - Elsevier
Linoleic acid (LA) is the most abundant polyunsaturated fatty acid found in the Western diet.
Cytochrome P450-derived LA metabolites 9, 10-epoxyoctadecenoic acid (9, 10-EpOME), 12 …
Cytochrome P450-derived LA metabolites 9, 10-epoxyoctadecenoic acid (9, 10-EpOME), 12 …
Therapeutic potential of omega-3 fatty acid-derived epoxyeicosanoids in cardiovascular and inflammatory diseases
WH Schunck, A Konkel, R Fischer… - Pharmacology & …, 2018 - Elsevier
Numerous benefits have been attributed to dietary long-chain omega-3 polyunsaturated fatty
acids (n-3 LC-PUFAs), including protection against cardiac arrhythmia, triglyceride-lowering …
acids (n-3 LC-PUFAs), including protection against cardiac arrhythmia, triglyceride-lowering …
Omega-3 fatty acid-derived mediators that control inflammation and tissue homeostasis
T Ishihara, M Yoshida, M Arita - International immunology, 2019 - academic.oup.com
Omega-3 polyunsaturated fatty acids (PUFAs), including eicosapentaenoic acid,
docosapentaenoic acid and docosahexaenoic acid, display a wide range of beneficial …
docosapentaenoic acid and docosahexaenoic acid, display a wide range of beneficial …
Omega-3 fatty acids and adipose tissue function in obesity and metabolic syndrome
L Martínez-Fernández, LM Laiglesia, AE Huerta… - Prostaglandins & other …, 2015 - Elsevier
The n-3 long-chain polyunsaturated fatty acids (n-3 PUFAs) such as eicosapentaenoic
(EPA) and docosahexaenoic (DHA) have been reported to improve obesity-associated …
(EPA) and docosahexaenoic (DHA) have been reported to improve obesity-associated …