Recent advances in experimental dendritic cell vaccines for cancer
The development of immunotherapeutic methods for the treatment of oncological diseases
have made it possible to improve the effectiveness of standard therapies. There was no …
have made it possible to improve the effectiveness of standard therapies. There was no …
The complex tumor microenvironment in ovarian cancer: therapeutic challenges and opportunities
B Garlisi, S Lauks, C Aitken, LM Ogilvie, C Lockington… - Current oncology, 2024 - mdpi.com
The tumor microenvironment (TME) in ovarian cancer (OC) has much greater complexity
than previously understood. In response to aggressive pro-angiogenic stimulus, blood …
than previously understood. In response to aggressive pro-angiogenic stimulus, blood …
Trial watch: Dendritic cell (DC)-based immunotherapy for cancer
Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable
development over recent decades. However, this field is currently in a state of flux toward …
development over recent decades. However, this field is currently in a state of flux toward …
Immunotherapy in ovarian cancer
N Siminiak, R Czepczyński, MP Zaborowski… - Archivum Immunologiae …, 2022 - Springer
Despite advances in surgery and chemotherapy, ovarian cancer remains one of the most
lethal malignancies. Hence, the implementation of novel treatment approaches is required to …
lethal malignancies. Hence, the implementation of novel treatment approaches is required to …
Integration of local and systemic immunity in ovarian cancer: Implications for immunotherapy
A Rajtak, M Ostrowska-Leśko, K Żak… - Frontiers in …, 2022 - frontiersin.org
Cancer is a disease that induces many local and systemic changes in immunity. The difficult
nature of ovarian cancer stems from the lack of characteristic symptoms that contributes to a …
nature of ovarian cancer stems from the lack of characteristic symptoms that contributes to a …
[HTML][HTML] Relationship between Th17 immune response and cancer
HS Marques, BB de Brito, FAF da Silva… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Cancer is the second leading cause of death worldwide and epidemiological projections
predict growing cancer mortality rates in the next decades. Cancer has a close relationship …
predict growing cancer mortality rates in the next decades. Cancer has a close relationship …
Dendritic cell vaccines: A promising approach in the fight against ovarian cancer
AA Caro, S Deschoemaeker, L Allonsius… - Cancers, 2022 - mdpi.com
Simple Summary With an overall 5-year survival of only 20% for advanced-stage ovarian
cancer patients, enduring and effective therapies are a highly unmet clinical need. Current …
cancer patients, enduring and effective therapies are a highly unmet clinical need. Current …
Dendritic cells: the yin and yang in disease progression
C Jimenez-Cortegana, F Palomares, G Alba… - Frontiers in …, 2024 - frontiersin.org
Dendritic cells (DCs) are antigen presenting cells that link innate and adaptive immunity.
DCs have been historically considered as the most effective and potent cell population to …
DCs have been historically considered as the most effective and potent cell population to …
Targeting the immune microenvironment for ovarian cancer therapy
F Blanc-Durand, L Clemence Wei Xian… - Frontiers in …, 2023 - frontiersin.org
Ovarian cancer (OC) is an aggressive malignancy characterized by a complex
immunosuppressive tumor microenvironment (TME). Immune checkpoint inhibitors have …
immunosuppressive tumor microenvironment (TME). Immune checkpoint inhibitors have …
The effects of dendritic cell-based vaccines in the tumor microenvironment: Impact on myeloid-derived suppressor cells
ML Sánchez-León, C Jiménez-Cortegana… - Frontiers in …, 2022 - frontiersin.org
Dendritic cells (DCs) are a heterogenous population of professional antigen presenting cells
whose main role is diminished in a variety of malignancies, including cancer, leading to …
whose main role is diminished in a variety of malignancies, including cancer, leading to …