Large language models in medicine

AJ Thirunavukarasu, DSJ Ting, K Elangovan… - Nature medicine, 2023 - nature.com
Large language models (LLMs) can respond to free-text queries without being specifically
trained in the task in question, causing excitement and concern about their use in healthcare …

Foundation models for generalist medical artificial intelligence

M Moor, O Banerjee, ZSH Abad, HM Krumholz… - Nature, 2023 - nature.com
The exceptionally rapid development of highly flexible, reusable artificial intelligence (AI)
models is likely to usher in newfound capabilities in medicine. We propose a new paradigm …

Scaling instruction-finetuned language models

HW Chung, L Hou, S Longpre, B Zoph, Y Tay… - Journal of Machine …, 2024 - jmlr.org
Finetuning language models on a collection of datasets phrased as instructions has been
shown to improve model performance and generalization to unseen tasks. In this paper we …

Sparks of artificial general intelligence: Early experiments with gpt-4

S Bubeck, V Chandrasekaran, R Eldan… - arXiv preprint arXiv …, 2023 - arxiv.org
Artificial intelligence (AI) researchers have been developing and refining large language
models (LLMs) that exhibit remarkable capabilities across a variety of domains and tasks …

A survey of large language models

WX Zhao, K Zhou, J Li, T Tang, X Wang, Y Hou… - arXiv preprint arXiv …, 2023 - arxiv.org
Language is essentially a complex, intricate system of human expressions governed by
grammatical rules. It poses a significant challenge to develop capable AI algorithms for …

Benefits, limits, and risks of GPT-4 as an AI chatbot for medicine

P Lee, S Bubeck, J Petro - New England Journal of Medicine, 2023 - Mass Medical Soc
Benefits, Limits, and Risks of GPT-4 as an AI Chatbot for Medicine | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Capabilities of gpt-4 on medical challenge problems

H Nori, N King, SM McKinney, D Carignan… - arXiv preprint arXiv …, 2023 - arxiv.org
Large language models (LLMs) have demonstrated remarkable capabilities in natural
language understanding and generation across various domains, including medicine. We …

BioGPT: generative pre-trained transformer for biomedical text generation and mining

R Luo, L Sun, Y Xia, T Qin, S Zhang… - Briefings in …, 2022 - academic.oup.com
Pre-trained language models have attracted increasing attention in the biomedical domain,
inspired by their great success in the general natural language domain. Among the two main …

A survey on evaluation of large language models

Y Chang, X Wang, J Wang, Y Wu, L Yang… - ACM Transactions on …, 2024 - dl.acm.org
Large language models (LLMs) are gaining increasing popularity in both academia and
industry, owing to their unprecedented performance in various applications. As LLMs …

The imperative for regulatory oversight of large language models (or generative AI) in healthcare

B Meskó, EJ Topol - NPJ digital medicine, 2023 - nature.com
The rapid advancements in artificial intelligence (AI) have led to the development of
sophisticated large language models (LLMs) such as GPT-4 and Bard. The potential …