Asthma—Genomic Advances Toward Risk Prediction

E Herrera-Luis, M Martin-Almeida… - Clinics in chest …, 2024 - chestmed.theclinics.com
Technological advances have accelerated discoveries in human genetics, including risk
variant identification, genetic risk prediction, and functional assessment of genetic variation …

Bioinformatic analysis of key regulatory genes in adult asthma and prediction of potential drug candidates

S Chen, J Lv, Y Luo, H Chen, S Ma, L Zhang - Molecules, 2023 - mdpi.com
Asthma is a common chronic disease that is characterized by respiratory symptoms
including cough, wheeze, shortness of breath, and chest tightness. The underlying …

[HTML][HTML] Integrated genomic network analysis revealed potential of a druggable target for hemorrhoid treatment

W Adikusuma, F Firdayani, LM Irham… - Saudi Pharmaceutical …, 2023 - Elsevier
Hemorrhoids are a prevalent medical condition that necessitates effective treatment options.
The current options for treatment consist of oral medications, topical applications, or surgery …

Differences in the DNA methylome of T cells in adults with asthma of varying severity

Y Liao, RG Cavalcante, JB Waller, F Deng… - Clinical …, 2024 - Springer
DNA methylation plays a critical role in asthma development, but differences in DNA
methylation among adults with varying asthma severity are less well-defined. To examine …

Comparison of Lung Tissue‐Derived Extracellular Vesicles Using Multiple Dissociation Methods for Profiling Protein Biomarkers

Y Han, M Ye, S Ye, B Liu - Biotechnology Journal, 2024 - Wiley Online Library
Extracellular vesicles (EVs) operate as chemical messengers that facilitate intercellular
communication. Emerging evidence has demonstrated that lung tissue‐derived EVs play …

Potential biomarker signatures in male infertility: integrative genomic analysis

D Junahar, R Dwiputri, W Adikusuma… - Egyptian Journal of …, 2024 - Springer
Background Studies have attributed 50% of infertility cases to male infertility, 15% of which is
caused by idiopathic genetic factors. Currently, no specific biomarkers have been revealed …

Genetic-driven biomarkers for liver fibrosis through bioinformatic approach

AJ Paulina, YV Mutiara, LM Irham, D Darmawi… - Egyptian Journal of …, 2024 - Springer
Background Liver fibrosis is a widespread chronic liver ailment linked to substantial mortality
and limited therapeutic options. An in-depth comprehension of the genetic underpinnings of …

Identification of Biomarker and Biological Risk Genes to Drive Drug Repurposing in Malaria Using Transcriptomics Database: Potential of Transcriptomic data to drive …

D Darmawi, W Adikusuma, LM Irham… - Iranian Journal of …, 2023 - theses.sbmu.ac.ir
This study applied the transcriptomic-based bioinformatics analysis to systematically
integrate data on risk loci for malaria biology and drug discovery from various databases. It …

Asthma-Genomic Advances Toward Risk

AT Risk - Pediatric Respiratory Disease, an Issue of Clinics in …, 2024 - books.google.com
• Genome-wide association studies of asthma have unraveled a wide catalog of common
variants associated with asthma with small to-moderate effect sizes. Further efforts should be …

[PDF][PDF] Repurposing drugs in endometrial cancer using genomic variants database

LM Irham, RRR Winarto, WA Fidiawati, A Nathania… - eprints.uad.ac.id
Globally, endometrial cancer (EC) is the six most common cancers related to female
reproductive. EC incidence and mortality rates have increased over the last decade …