The presence of estrogen receptors (ERs), as detected by immunohistochemistry (IHC), is a
weak prognostic marker of clinical outcome in breast cancer, but a strong predictive marker …

Introduction Accurate assessment of estrogen receptor (ER), progesterone receptor (PR),
and Ki-67 is essential in the histopathologic diagnostics of breast cancer. Commercially …

The PET compound 18F-fluoroestradiol (18F-FES) has been developed and tested as an
agent for the imaging of estrogen receptor (ER) expression in vivo. 18F-FES uptake has …

Assessment of hormone receptors (estrogen and progesterone) helps to direct therapy for
women with breast cancer. Immunohistochemistry is most commonly used to assess …

Context.—Observer variability in digital microscopy and the effect of computer-aided digital
microscopy are underexamined areas in need of further research, considering the …

Background: Image analysis of tissue sections using RGB image profiling is a modern
accepted technique. Materials and Methods: A new method of RGB analysis, using the …

Quantification of protein expression based on immunohistochemistry (IHC) is an important
step for translational research and clinical routine. Several manual ('eyeballing') scoring …

The purpose of this prospective study was to investigate whether correlations exist between
18F-FDG uptake of primary breast cancer lesions and predictive and prognostic factors such …

Abstract Background: Estrogen receptor (ER), progesterone receptor (PR) and human
epidermal growth factor receptor-2 (HER2) are important and well-established prognostic …

Background: A major challenge in studies of etiologic heterogeneity in breast cancer has
been the limited throughput, accuracy, and reproducibility of measuring tissue markers …