Systemic autoimmune diseases are characterized by the failure of the immune system to
differentiate self from non-self. These conditions are associated with significant morbidity …

SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …

The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

Multiple organ dysfunction is the most severe outcome of sepsis progression and is highly
correlated with a worse prognosis. Excessive neutrophil extracellular traps (NETs) are …

Dysregulated neutrophil activation contributes to the pathogenesis of autoimmune diseases
including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Neutrophil …

Rheumatoid arthritis (RA) is a chronic inflammatory disorder affecting synovial joints.
Neutrophils are believed to play an important role in both the initiation and progression of …

Modulation of neutrophil recruitment and function is crucial for targeting inflammatory cells to
sites of infection to combat invading pathogens while, at the same time, limiting host tissue …

Evidence shows that neutrophils can protect the host against pathogens in multiple ways,
including the formation and release of neutrophil extracellular traps (NETs). NETs are web …

Background The release of neutrophil extracellular traps (NETs) is associated with
inflammation, coagulopathy, and organ damage found in severe cases of COVID-19 …

Active neutrophils participate in innate and adaptive immune responses through various
mechanisms, one of the most important of which is the formation and release of neutrophil …