Dravet syndrome: A systematic literature review of the illness burden
A Strzelczyk, L Lagae, JM Wilmshurst… - Epilepsia …, 2023 - Wiley Online Library
We performed a systematic literature review and narrative synthesis according to a pre‐
registered protocol (Prospero: CRD42022376561) to identify the evidence associated with …
registered protocol (Prospero: CRD42022376561) to identify the evidence associated with …
[HTML][HTML] Genetic variations in GABA metabolism and epilepsy
Y Feng, ZH Wei, C Liu, GY Li, XZ Qiao, YJ Gan… - Seizure, 2022 - Elsevier
Epilepsy is a paroxysmal brain disorder that results from an imbalance between neuronal
excitation and inhibition. Gamma-aminobutyric acid (GABA) is the most important inhibitory …
excitation and inhibition. Gamma-aminobutyric acid (GABA) is the most important inhibitory …
[HTML][HTML] EpilepsyNet: Novel automated detection of epilepsy using transformer model with EEG signals from 121 patient population
Background Epilepsy is one of the most common neurological conditions globally, and the
fourth most common in the United States. Recurrent non-provoked seizures characterize it …
fourth most common in the United States. Recurrent non-provoked seizures characterize it …
The burden of illness in Lennox–Gastaut syndrome: a systematic literature review
Abstract Background Lennox–Gastaut syndrome (LGS) is a severe developmental and
epileptic encephalopathy characterized by drug-resistant epilepsy with multiple seizure …
epileptic encephalopathy characterized by drug-resistant epilepsy with multiple seizure …
Management of epileptic disorders using nanotechnology-based strategies for nose-to-brain drug delivery
Introduction Epilepsy, a major neurological disorder affects about 1% of the Indian
population. The discovery of noninvasive strategies for epilepsy presents a challenge for the …
population. The discovery of noninvasive strategies for epilepsy presents a challenge for the …
Advances in the mTOR signaling pathway and its inhibitor rapamycin in epilepsy
W Zhao, C Xie, X Zhang, J Liu, J Liu… - Brain and Behavior, 2023 - Wiley Online Library
Introduction Epilepsy is one of the most common and serious brain syndromes and has
adverse consequences on a patient's neurobiological, cognitive, psychological, and social …
adverse consequences on a patient's neurobiological, cognitive, psychological, and social …
The contribution of HCN channelopathies in different epileptic syndromes, mechanisms, modulators, and potential treatment targets: a systematic review
M Kessi, J Peng, H Duan, H He, B Chen… - Frontiers in Molecular …, 2022 - frontiersin.org
Background Hyperpolarization-activated cyclic nucleotide-gated (HCN) current reduces
dendritic summation, suppresses dendritic calcium spikes, and enables inhibitory GABA …
dendritic summation, suppresses dendritic calcium spikes, and enables inhibitory GABA …
The metabolic role of ketogenic diets in treating epilepsy
K Imdad, T Abualait, A Kanwal, ZT AlGhannam… - Nutrients, 2022 - mdpi.com
Epilepsy is a long-term neurological condition that results in recurrent seizures.
Approximately 30% of patients with epilepsy have drug-resistant epilepsy (DRE). The …
Approximately 30% of patients with epilepsy have drug-resistant epilepsy (DRE). The …
Esculetin alleviates pentylenetetrazole-induced seizures, cognitive impairment and pro-inflammatory cytokines and suppresses penicillin-induced epileptiform activity …
Aims To investigate the effects of different doses of esculetin on epileptiform activity,
behavioral seizures, memory impairment, and cortical and hippocampal NF-κB, as a …
behavioral seizures, memory impairment, and cortical and hippocampal NF-κB, as a …
Anticonvulsant effect of quercetin in pentylenetetrazole (PTZ)-induced seizures in male mice: The role of anti-neuroinflammatory and anti-oxidative stress
Z Tavakoli, HT Dehkordi, Z Lorigooini… - International …, 2023 - Elsevier
Background Epilepsy is one of the major neurological disorders. The inflammatory process
and oxidative stress are closely related to seizure progression. Quercetin is a flavonoid with …
and oxidative stress are closely related to seizure progression. Quercetin is a flavonoid with …