[HTML][HTML] Peroxisome proliferator-activated receptors: Experimental targeting for the treatment of inflammatory bowel diseases
J Decara, P Rivera, AJ López-Gambero… - Frontiers in …, 2020 - frontiersin.org
The peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor
proteins that promote ligand-dependent transcription of target genes that regulate energy …
proteins that promote ligand-dependent transcription of target genes that regulate energy …
5-HT3 receptor antagonists in neurologic and neuropsychiatric disorders: the iceberg still lies beneath the surface
5-HT3 receptor antagonists, first introduced to the market in the mid-1980s, are proven
efficient agents to counteract chemotherapy-induced emesis. Nonetheless, recent …
efficient agents to counteract chemotherapy-induced emesis. Nonetheless, recent …
[HTML][HTML] Luteolin alleviates inflammation and modulates gut microbiota in ulcerative colitis rats
B Li, P Du, Y Du, D Zhao, Y Cai, Q Yang, Z Guo - Life sciences, 2021 - Elsevier
Ulcerative colitis (UC) is a chronic inflammatory bowel disease related to intestinal
dysbiosis. Luteolin has been reported to reduce inflammation. However, it remains unclear …
dysbiosis. Luteolin has been reported to reduce inflammation. However, it remains unclear …
Recent advances with 5‐HT3 modulators for neuropsychiatric and gastrointestinal disorders
R Juza, P Vlcek, E Mezeiova, K Musilek… - Medicinal research …, 2020 - Wiley Online Library
Abstract Serotonin (5‐hydroxytryptophan [5‐HT]) is a biologically active amine expressed in
platelets, in gastrointestinal (GI) cells and, to a lesser extent, in the central nervous system …
platelets, in gastrointestinal (GI) cells and, to a lesser extent, in the central nervous system …
[HTML][HTML] Interventions of natural and synthetic agents in inflammatory bowel disease, modulation of nitric oxide pathways
Inflammatory bowel disease (IBD) refers to a group of disorders characterized by chronic
inflammation of the gastrointestinal (GI) tract. The elevated levels of nitric oxide (NO) in …
inflammation of the gastrointestinal (GI) tract. The elevated levels of nitric oxide (NO) in …
Gliclazide attenuates acetic acid-induced colitis via the modulation of PPARγ, NF-κB and MAPK signaling pathways
ESA Arafa, WR Mohamed, DM Zaher… - Toxicology and applied …, 2020 - Elsevier
Ulcerative Colitis is a universal autoimmune disease with high incidence rates worldwide. It
is characterized by the existence of many other concurrent immune-associated ailments …
is characterized by the existence of many other concurrent immune-associated ailments …
[HTML][HTML] The abilities of salidroside on ameliorating inflammation, skewing the imbalanced nucleotide oligomerization domain-like receptor family pyrin domain …
J Liu, J Cai, P Fan, N Zhang, Y Cao - Frontiers in pharmacology, 2019 - frontiersin.org
Salidroside (Sal), as a major glycoside extracted from Rhodiola rosea L., has exhibited its
mighty anti-aging, anti-oxidant, anti-cancer, anti-inflammation, and neuroprotective effects in …
mighty anti-aging, anti-oxidant, anti-cancer, anti-inflammation, and neuroprotective effects in …
Administration of geniposide ameliorates dextran sulfate sodium-induced colitis in mice via inhibition of inflammation and mucosal damage
Z Zhang, Y Li, P Shen, S Li, X Lu, J Liu, Y Cao… - International …, 2017 - Elsevier
Ulcerative colitis (UC), an idiopathic inflammatory bowel disease, not only affects millions of
patients worldwide, but also increases the risk of colon cancer. Geniposide is an iridoid …
patients worldwide, but also increases the risk of colon cancer. Geniposide is an iridoid …
Pingwei San ameliorates dextran sulfate sodium-induced chronic colitis in mice
Z Zhang, P Shen, W Xie, H Cao, J Liu, Y Cao… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance Ping weisan (PWS), a famous traditional Chinese
medicinal, is published in the Prescriptions of Taiping Benevolent Dispensary. PWS has …
medicinal, is published in the Prescriptions of Taiping Benevolent Dispensary. PWS has …
Tropisetron ameliorates cyclophosphamide-induced hemorrhagic cystitis in rats
Hemorrhagic cystitis is one of the most important complications of cyclophosphamide, a drug
widely used in cancer chemotherapy and bone marrow transplantation. 5-HT 3 antagonists …
widely used in cancer chemotherapy and bone marrow transplantation. 5-HT 3 antagonists …