Vertebrate hemoglobin (Hb) and myoglobin (Mb) were among the first proteins whose
structures and sequences were determined over 50 years ago. In the subsequent …

Over the years strong evidence has been accumulated showing that aerobic physical
exercise exerts beneficial effects on the prevention and reduction of cardiovascular risk …

Cancer progression is an intricate biological process profiled by not only unscheduled
proliferation, but also altered metabolism mechanisms. In this article, we introduced a novel …

Food synergy concept is suggested to explain observations that isolated antioxidants are
less bioactive than real foods containing them. However, mechanisms behind this …

Impaired diabetic wounds are one of the major pathophysiological complications caused by
persistent microbial infections, prolonged inflammation, and insufficient angiogenic …

Redox homeostasis involves factors that ensure proper function of cells. The excess reactive
oxygen species (ROS) leads to oxidative stress and increased risk of oxidative damage to …

Introduction Cyclophosphamide (CP) causes redox imbalance and its use is associated with
marked cardiotoxicity that limits its clinical applications. The present study investigated the …

Despite recent advances in melanoma treatment, there are still patients that either do not
respond or develop resistance. This unresponsiveness and/or acquired resistance to …

Exercise training reduces renin-angiotensin system (RAS) activation, decreases plasma and
tissue oxidative stress and inflammation in hypertension. However, the temporal nature of …

Cytoglobin is an evolutionary ancient hemoglobin with poor functional annotation. Rather
than constrained to penta coordination, cytoglobin's heme iron may exist either as a penta or …