Abstract inflammation is a process that plays an important role in the initiation and
progression of atherosclerosis and immune disease, involving multiple cell types, including …

Statins are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors used
worldwide to manage dyslipidaemia and thus limit the development of atherosclerotic …

Background Statins have pleiotropic immunomodulatory effects that may be beneficial in the
treatment of asthma. We previously reported that treatment with atorvastatin improved …

Macrophages undergo activation by pathophysiological stimuli to pro-inflammatory and
bactericidal, or wound-healing and anti-inflammatory phenotypes, termed M1 or M2 …

Statins, also known as HMG-CoA reductase inhibitors, are widely prescribed drugs for the
prevention and treatment of cardiovascular diseases. In addition to their lipid-lowering …

Xuezhikang capsule (XZK) is a traditional Chinese medicine that contains lovastatin (Lv) for
hyperlipidemia treatment, although it has fewer side effects than Lv. However, the …

Monacolin K (MK) is a naturally occurring hypocholesterolemic agent that specifically
inhibits HMG‐C o A reductase. As a natural source of MK, Monascus‐fermented products …

Abstract Background/Aims: Mevalonate Kinase Deficiency (MKD), is a hereditary disease
due to mutations in mevalonate kinase gene (MVK). MKD has heterogeneous clinical …

Oxidative stress hurts the survival of transplanted mesenchymal stem cells (MSCs).
Lipopolysaccharide (LPS) preconditioning inhibits apoptotic death in MSCs. Also …

Mevalonate kinase deficiency is a rare disease whose worst manifestation, characterised by
severe neurologic impairment, is called mevalonic aciduria. The progressive neuronal loss …