The role of selected pro-inflammatory cytokines in pathogenesis of ischemic stroke
Stroke is currently one of the most common causes of death and disability in the world, and
its pathophysiology is a complex process, involving the oxidative stress and inflammatory …
its pathophysiology is a complex process, involving the oxidative stress and inflammatory …
Systemic inflammation as a therapeutic target in acute ischemic stroke
T Dziedzic - Expert review of neurotherapeutics, 2015 - Taylor & Francis
Acute systemic inflammatory reaction superimposed on chronic low-grade inflammation
accompanies acute ischemic stroke. Elevated blood levels of systemic inflammatory markers …
accompanies acute ischemic stroke. Elevated blood levels of systemic inflammatory markers …
RNA-Seq identifies circulating miR-125a-5p, miR-125b-5p, and miR-143-3p as potential biomarkers for acute ischemic stroke
Rationale: Currently, there are no blood-based biomarkers with clinical utility for acute
ischemic stroke (IS). MicroRNAs show promise as disease markers because of their cell type …
ischemic stroke (IS). MicroRNAs show promise as disease markers because of their cell type …
Inflammatory molecules might become both biomarkers and therapeutic targets for stroke management
L Ramiro, A Simats… - Therapeutic …, 2018 - journals.sagepub.com
Stroke is the fifth leading cause of death and the most frequent cause of disability worldwide.
Currently, stroke diagnosis is based on neuroimaging; therefore, the lack of a rapid tool to …
Currently, stroke diagnosis is based on neuroimaging; therefore, the lack of a rapid tool to …
[HTML][HTML] The role of CCL2/CCR2 axis in cerebral ischemia-reperfusion injury and treatment: from animal experiments to clinical trials
H Geng, L Chen, J Tang, Y Chen, L Wang - International journal of …, 2022 - mdpi.com
CC motif chemokine ligand 2 (CCL2) is a member of the monocyte chemokine protein
family, which binds to its receptor CCR2 to induce monocyte infiltration and mediate …
family, which binds to its receptor CCR2 to induce monocyte infiltration and mediate …
Chemokines in CNS injury and repair
A Jaerve, HW Müller - Cell and tissue research, 2012 - Springer
Recruitment of inflammatory cells is known to drive the secondary damage cascades that
are common to injuries of the central nervous system (CNS). Cell activation and infiltration to …
are common to injuries of the central nervous system (CNS). Cell activation and infiltration to …
Prognostic value of blood interleukin-6 in the prediction of functional outcome after stroke: a systematic review and meta-analysis
A Bustamante, T Sobrino, D Giralt… - Journal of …, 2014 - Elsevier
We aimed to quantify the association of blood interleukin-6 (IL-6) concentrations with poor
outcome after stroke and its added predictive value over clinical information. Meta-analysis …
outcome after stroke and its added predictive value over clinical information. Meta-analysis …
Elevated concentrations of inflammation-related proteins in postnatal blood predict severe developmental delay at 2 years of age in extremely preterm infants
OBJECTIVE: To evaluate the hypothesis that elevated levels of inflammation-related
proteins in early postnatal blood predict impaired mental and motor development in …
proteins in early postnatal blood predict impaired mental and motor development in …
[HTML][HTML] Inflammation, anti-inflammatory interventions, and post-stroke cognitive impairment: a systematic review and Meta-analysis of human and animal studies
RWP Tack, C Amboni, D van Nuijs, M Pekna… - Translational Stroke …, 2023 - Springer
The pathophysiology and treatment of post-stroke cognitive impairment (PSCI) are not clear.
Stroke triggers an inflammatory response, which might affect synapse function and cognitive …
Stroke triggers an inflammatory response, which might affect synapse function and cognitive …
Interleukin-33 ameliorates ischemic brain injury in experimental stroke through promoting Th2 response and suppressing Th17 response
YI Luo, Y Zhou, W Xiao, Z Liang, J Dai, X Weng, X Wu - Brain research, 2015 - Elsevier
Ischemic stroke causes brain injury with activation of an inflammatory response that can
contribute to clinical impairment. As a novel cytokine of the interleukin-1 (IL-1) family, IL-33 …
contribute to clinical impairment. As a novel cytokine of the interleukin-1 (IL-1) family, IL-33 …