Neurofilament proteins as biomarkers to monitor neurological diseases and the efficacy of therapies
Biomarkers of neurodegeneration and neuronal injury have the potential to improve
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …
Neurofilaments and neurofilament proteins in health and disease
Neurofilaments (NFs) are unique among tissue-specific classes of intermediate filaments
(IFs) in being heteropolymers composed of four subunits (NF-L [neurofilament light]; NF-M …
(IFs) in being heteropolymers composed of four subunits (NF-L [neurofilament light]; NF-M …
Increased neurofilament light chain blood levels in neurodegenerative neurological diseases
Objective Neuronal damage is the morphological substrate of persisting neurological
disability. Neurofilaments (Nf) are cytoskeletal proteins of neurons and their release into …
disability. Neurofilaments (Nf) are cytoskeletal proteins of neurons and their release into …
Serum neurofilament is associated with progression of brain atrophy and disability in early MS
Objective: To investigate a potential effect of riluzole on serum neurofilaments (Nf) compared
to placebo and the relationship between longitudinal clinical and MRI outcomes and serum …
to placebo and the relationship between longitudinal clinical and MRI outcomes and serum …
Comprehensive characterization and failure modes of tungsten microwire arrays in chronic neural implants
For nearly 55 years, tungsten microwires have been widely used in neurophysiological
experiments in animal models to chronically record neuronal activity. While tungsten …
experiments in animal models to chronically record neuronal activity. While tungsten …
Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects
FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …
provides a comprehensive and up-to-date account on the latest developments in the area of …
Diagnostic and prognostic performance of neurofilaments in ALS
K Poesen, P Van Damme - Frontiers in neurology, 2019 - frontiersin.org
There is a need for biomarkers for amyotrophic lateral sclerosis (ALS), to support the
diagnosis of the disease, to predict disease progression and to track disease activity and …
diagnosis of the disease, to predict disease progression and to track disease activity and …
Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome
Background Neurofilaments (Nf) are major structural proteins that occur exclusively in
neurons. In spinal cord injury (SCI), the severity of disease is quantified by clinical measures …
neurons. In spinal cord injury (SCI), the severity of disease is quantified by clinical measures …
[图书][B] The handbook of biomarkers
KK Jain, KK Jain - 2010 - Springer
There are several definitions of biomarkers. A biomarker is a characteristic that can be
objectively measured and evaluated as an indicator of a physiological as well as a …
objectively measured and evaluated as an indicator of a physiological as well as a …
[HTML][HTML] Morphologic features and glial activation in rat oxaliplatin-dependent neuropathic pain
LDC Mannelli, A Pacini, L Bonaccini, M Zanardelli… - The Journal of …, 2013 - Elsevier
Neurotoxicity is the limiting side effect of the anticancer agent oxaliplatin. A tangled panel of
symptoms, sensory loss, paresthesia, dysesthesia, and pain may be disabling for patients …
symptoms, sensory loss, paresthesia, dysesthesia, and pain may be disabling for patients …