Recently the World Health Organization (WHO), in collaboration with the European
Association for Haematopathology and the Society for Hematopathology, published a …

This review examines the evidence that bone marrow failure (BMF) in aplastic anaemia (AA)
is due to loss of haematopoietic stem cells (HSC s), which, in turn, is caused by deranged …

Context In most patients, aplastic anemia results from T-cell–mediated immune destruction
of bone marrow. Aplastic anemia can be effectively treated by stem cell transplantation or …

In aplastic anemia, hematopoiesis fails: Blood cell counts are extremely low, and the bone
marrow appears empty. The pathophysiology of aplastic anemia is now believed to be …

The myelodysplastic syndromes (MDSs) are characterized by bilineage or trilineage
dysplasia. Although diagnostic criteria are well established for MDS, a significant number of …

The extent and importance of autoimmune mechanisms in myelodysplastic syndrome (MDS)
and the role of immunosuppression in the treatment of this disease are not well defined. We …

New-onset pancytopenia can be caused by a wide variety of etiologies, leading to a
diagnostic dilemma. These etiologies range from congenital bone marrow failure to marrow …

The myelodysplastic syndromes (MDS) are characterized by hemopoietic insufficiency
associated with cytopenias leading to serious morbidity plus the additional risk of leukemic …

Detection of dysmorphic cells in peripheral blood (PB) smears is essential in diagnostic
screening of hematological diseases. Myelodysplastic syndromes (MDS) are hematopoietic …

Secondary acute myeloid leukemia (s-AML) includes therapy-related AML and AML
evolving from antecedent hematological disorder (AHD). s-AML arising after treating AHD …