Cattle ticks are an important constraint on livestock production, particularly in tropical and
subtropical areas. Use of synthetic acaricides is the primary method of tick control; therefore …

There is an on-going need for the discovery and development of new pesticides due to the
loss of existing products through the continuing development of resistance, the desire for …

Dopamine is an important catecholamine neurotransmitter in invertebrates and vertebrates.
It is biochemically derived from tyrosine via L-DOPA. It is most abundant in the central …

G-protein coupled receptors (GPCRs) play important roles in cell biology and insects'
physiological processes, toxicological response and the development of insecticide …

G-protein-coupled receptors regulate signal transduction pathways and play diverse and
pivotal roles in the physiology of insects, however, the precise function of GPCRs in …

Female yellow-fever mosquitoes, Aedes aegypti, are obligate blood-feeders and vectors of
the pathogens that cause dengue fever, yellow fever and Chikungunya. This feeding …

Highlights•Arthropod GPCRs are targets for development of novel mode of action
pesticides.•Genome sequence has enabled the identification of GPCRs from multiple …

G protein-coupled receptors (GPCRs), which regulate numerous intracellular signaling
cascades that mediate many essential physiological processes, are attractive yet …

Insecticide resistance amongst disease vectors is a growing problem and novel compounds
are needed. Biogenic amines are important for neurotransmission and we have recently …

The discovery and development of new active ingredients to control arthropod populations
and circumvent the inevitable evolution of insecticide resistance has been of consistent …