Global burden of atherosclerotic cardiovascular disease in people living with HIV: systematic review and meta-analysis

ASV Shah, D Stelzle, KK Lee, EJ Beck, S Alam… - Circulation, 2018 - Am Heart Assoc
Background: With advances in antiretroviral therapy, most deaths in people with HIV are
now attributable to noncommunicable illnesses, especially cardiovascular disease. We …

Innate immune receptors in platelets and platelet-leukocyte interactions

PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

[HTML][HTML] Lymphopenia in cancer patients and its effects on response to immunotherapy: an opportunity for combination with cytokines?

C Ménétrier-Caux, I Ray-Coquard, JY Blay… - … for immunotherapy of …, 2019 - Springer
Quantitative lymphocyte alterations are frequent in patients with cancer, and strongly impact
prognosis and survival. The development of cancers in immunosuppressed patients has …

[HTML][HTML] Platelets in immune response to virus and immunopathology of viral infections

ED Hottz, FA Bozza, PT Bozza - Frontiers in medicine, 2018 - frontiersin.org
Platelets are essential effector cells in hemostasis. Aside from their role in coagulation,
platelets are now recognized as major inflammatory cells with key roles in the innate and …

Evolving epidemiology of HIV-associated malignancies

MS Shiels, EA Engels - Current Opinion in HIV and AIDS, 2017 - journals.lww.com
The epidemiology of cancer among HIV-infected people has evolved since the beginning of
the HIV epidemic with particularly marked changes since the introduction of modern …

Causes of death in HIV-1—infected patients treated with antiretroviral therapy, 1996–2006: collaborative analysis of 13 HIV cohort studies

Antiretroviral Therapy Cohort … - Clinical Infectious …, 2010 - academic.oup.com
Background. We examined specific causes of mortality in human immunodeficiency virus
type 1 (HIV-1)—infected patients who initiated antiretroviral therapy (ART) in Europe and …

Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy

T Le, EJ Wright, DM Smith, W He… - … England Journal of …, 2013 - Mass Medical Soc
Background The relationship between the timing of the initiation of antiretroviral therapy
(ART) after infection with human immunodeficiency virus type 1 (HIV-1) and the recovery of …

Residual immune dysregulation syndrome in treated HIV infection

MM Lederman, NT Funderburg, RP Sekaly… - Advances in …, 2013 - Elsevier
Antiretroviral therapy has revolutionized the course of HIV infection, improving immune
function and decreasing dramatically the mortality and morbidity due to the opportunistic …

Impact of late diagnosis and treatment on life expectancy in people with HIV-1: UK Collaborative HIV Cohort (UK CHIC) Study

M May, M Gompels, V Delpech, K Porter, F Post… - Bmj, 2011 - bmj.com
Objectives To estimate life expectancy for people with HIV undergoing treatment compared
with life expectancy in the general population and to assess the impact on life expectancy of …

Effect of immunodeficiency, HIV viral load, and antiretroviral therapy on the risk of individual malignancies (FHDH-ANRS CO4): a prospective cohort study

M Guiguet, F Boué, J Cadranel, JM Lang… - The lancet …, 2009 - thelancet.com
Background The relative roles of immunodeficiency, HIV viral load, and combination
antiretroviral therapy (cART) in the onset of individual cancers have rarely been examined …