Manufacturing, characterization and control of cell-based medicinal products: challenging paradigms toward commercial use

P Salmikangas, M Menezes-Ferreira… - Regenerative …, 2015 - Taylor & Francis
During the past decade, a large number of cell-based medicinal products have been tested
in clinical trials for the treatment of various diseases and tissue defects. However, licensed …

Silica‐coated magnetic nanoparticles labeled endothelial progenitor cells alleviate ischemic myocardial injury and improve long‐term cardiac function with magnetic …

B Zhang, H Jiang, J Chen, Q Hu… - Journal of Cellular …, 2019 - Wiley Online Library
Low retention of endothelial progenitor cells (EPCs) in the infarct area has been suggested
to be responsible for the poor clinical efficacy of EPC therapy for myocardial infarction (MI) …

(Re-) programming of subtype specific cardiomyocytes

F Hausburg, JJ Jung, M Hoch, M Wolfien… - Advanced Drug Delivery …, 2017 - Elsevier
Adult cardiomyocytes (CMs) possess a highly restricted intrinsic regenerative potential—a
major barrier to the effective treatment of a range of chronic degenerative cardiac disorders …

[HTML][HTML] Trichosanthes pericarpium Aqueous Extract Enhances the Mobilization of Endothelial Progenitor Cells and Up-regulates the Expression of VEGF, eNOS, NO …

N Fu, H Li, J Sun, L Xun, D Gao, Q Zhao - Frontiers in Physiology, 2018 - frontiersin.org
Trichosanthes pericarpium (TP) had been widely used to cure patients of cardiovascular
disease for 2,000 years in China. This study aims to extend our previous work to explore the …

Specific cell (re-) programming: approaches and perspectives

F Hausburg, JJ Jung, R David - … and Application of Pluripotent Stem Cells, 2018 - Springer
Many disorders are manifested by dysfunction of key cell types or their disturbed integration
in complex organs. Thereby, adult organ systems often bear restricted self-renewal potential …

Fractionation of embryonic cardiac progenitor cells and evaluation of their differentiation potential

T Feridooni, KBS Pasumarthi - Differentiation, 2019 - Elsevier
Mid-gestation mouse ventricles (E11. 5) contain a larger number of Nkx2. 5+ cardiac
progenitor cells (CPCs). The proliferation rates are consistently higher in CPCs compared to …

GLP: A requirement in cell therapies-perspectives for the cardiovascular field

U Müller-Ruch, A Skorska, H Lemcke… - Advanced drug delivery …, 2020 - Elsevier
In biomedical research, enormous progress is being made and new candidates for putative
medicinal products emerge. However, most published preclinical data are not conducted …

[引用][C] 瑞舒伐他汀动员内皮祖细胞对心肌梗死患者心功能的影响

陈淑娴, 李许林, 孙婷 - 浙江实用医学, 2016

[引用][C] Optimisation of stem cell based approaches towards cardiac regeneration

F Thiele - 2019 - Dissertation, Rostock, Universität …

[引用][C] Hücrelerinden Arındırılmış Miyokardiyal Doku İle Hücre Tabakası Destekli Kalp Yaması Geliştirilmesi

G Kaynak Bayrak - 2019 - Fen Bilimleri Enstitüsü