Pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer,
has a median overall survival of 6–12 months and a 5-year survival of less than 7%. While …

Metastasis and tumor progression are the major cause of death in patients suffering from
pancreatic ductal adenocarcinoma. Tumor growth and especially dissemination are typically …

Cancer stem cells (CSCs) are thought to drive tumor growth, metastasis and
chemoresistance. Although surface markers such as CD133 and CD44 have been …

Cancer stem cells (CSC) are thought to play a major role in the development and metastatic
progression of pancreatic ductal adenocarcinoma (PDAC), one of the deadliest solid tumors …

Pancreatic Ductal Adenocarcinoma (PDAC) is the fourth most common cause of cancer-
related death and is the most lethal of common malignancies with a five-year survival rate …

Pancreatic ductal adenocarcinoma is one of the deadliest carcinomas and is characterized
by highly tumorigenic and metastatic cancer stem cells (CSC). CSCs evade available …

Pancreatic neoplasms are morphologically and genetically heterogeneous and include a
wide variety of tumors ranging from benign to malignant with an extremely poor clinical …

A better molecular understanding of gastrointestinal cancers arising either from the stomach,
the pancreas, the intestine, or the liver has led to the identification of a variety of potential …

Cancer stem cells (CSCs) have attracted much attention of the research community in the
recent years. Due to their highly tumorigenic and drug-resistant properties, CSCs represent …

Almost all tumors are composed of a heterogeneous cell population, making them difficult to
treat. A small cancer stem cell population with a low proliferation rate and a high tumorigenic …