New developments in RiPP discovery, enzymology and engineering
M Montalbán-López, TA Scott, S Ramesh… - Natural product …, 2021 - pubs.rsc.org
Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …
[HTML][HTML] A review of hybrid renewable energy systems in mini-grids for off-grid electrification in developing countries
EIC Zebra, HJ van der Windt, G Nhumaio… - … and Sustainable Energy …, 2021 - Elsevier
Rural communities in developing countries lack access to affordable, reliable, and
sustainable forms of energy, which are essential factors for improving living conditions …
sustainable forms of energy, which are essential factors for improving living conditions …
[PDF][PDF] After a century of nisin research-where are we now?
D Field, M Fernandez de Ullivarri… - FEMS microbiology …, 2023 - academic.oup.com
It is almost a century since nisin was discovered in fermented milk cultures, coincidentally in
the same year that penicillin was first described. Over the last 100 years this small, highly …
the same year that penicillin was first described. Over the last 100 years this small, highly …
Increasing the antimicrobial activity of nisin-based lantibiotics against Gram-negative pathogens
Q Li, M Montalban-Lopez… - Applied and environmental …, 2018 - Am Soc Microbiol
Lantibiotics are ribosomally synthesized and posttranslationally modified antimicrobial
compounds containing lanthionine and methyl-lanthionine residues. Nisin, one of the most …
compounds containing lanthionine and methyl-lanthionine residues. Nisin, one of the most …
Lipidated variants of the antimicrobial peptide nisin produced via incorporation of methionine analogs for click chemistry show improved bioactivity
L Guo, C Wang, J Broos, OP Kuipers - Journal of Biological Chemistry, 2023 - ASBMB
The increase in antibiotic resistance calls for accelerated molecular engineering strategies
to diversify natural products for drug discovery. The incorporation of non-canonical amino …
to diversify natural products for drug discovery. The incorporation of non-canonical amino …
Analysis of modular bioengineered antimicrobial lanthipeptides at nanoliter scale
S Schmitt, M Montalbán-López, D Peterhoff… - Nature chemical …, 2019 - nature.com
The rise of antibiotic resistance demands the acceleration of molecular diversification
strategies to inspire new chemical entities for antibiotic medicines. We report here on the …
strategies to inspire new chemical entities for antibiotic medicines. We report here on the …
Therapeutic application of lantibiotics and other lanthipeptides: old and new findings
Lanthipeptides are ribosomally synthesized and posttranslationally modified peptides, with
modifications that are incorporated during biosynthesis by dedicated enzymes. Various …
modifications that are incorporated during biosynthesis by dedicated enzymes. Various …
Rombocin, a Short Stable Natural Nisin Variant, Displays Selective Antimicrobial Activity against Listeria monocytogenes and Employs a Dual Mode of Action to Kill …
Nisin, with its unique mode of action and potent antimicrobial activity, serves as a
remarkable inspiration for the design of novel antibiotics. However, peptides possess …
remarkable inspiration for the design of novel antibiotics. However, peptides possess …
Cesin, a short natural variant of nisin, displays potent antimicrobial activity against major pathogens despite lacking two C-terminal macrocycles
Nisin is a widely used lantibiotic owing to its potent antimicrobial activity and its food-grade
status. Its mode of action includes cell wall synthesis inhibition and pore formation, which …
status. Its mode of action includes cell wall synthesis inhibition and pore formation, which …
Nisin S, a Novel Nisin Variant Produced by Ligilactobacillus salivarius P1CEA3
Recently, the food industry and the animal farming field have been working on different
strategies to reduce the use of antibiotics in animal production. The use of probiotic …
strategies to reduce the use of antibiotics in animal production. The use of probiotic …