Immunological impacts of diabetes on the susceptibility of Mycobacterium tuberculosis

B Ayelign, M Negash, M Genetu… - Journal of …, 2019 - Wiley Online Library
The interaction between diabetes and major world infections like TB is a major public health
concern because of rapidly rising levels of diabetes. The dual burden of tuberculosis (TB) …

Diabetes and tuberculosis

BI Restrepo - Understanding the host immune response against …, 2018 - Springer
The worldwide increase in the prevalence of diabetes has been most notable in TB-endemic
countries and has led to the re-emerging importance of the association between these two …

Influence of diabetes mellitus on immunity to human tuberculosis

P Kumar Nathella, S Babu - Immunology, 2017 - Wiley Online Library
Type 2 diabetes mellitus (DM) is a major risk factor for the development of active pulmonary
tuberculosis (TB), with development of DM pandemic in countries where TB is also endemic …

Intestinal microbiota: a new force in cancer immunotherapy

Z Dai, J Zhang, Q Wu, H Fang, C Shi, Z Li, C Lin… - Cell Communication and …, 2020 - Springer
Cancer displays high levels of heterogeneity and mutation potential, and curing cancer
remains a challenge that clinicians and researchers are eager to overcome. In recent years …

Plasma proinflammatory cytokines are markers of disease severity and bacterial burden in pulmonary tuberculosis

NP Kumar, K Moideen, VV Banurekha… - Open forum …, 2019 - academic.oup.com
Abstract Background Type 1, type 17, and other proinflammatory cytokines are important in
host immunity to tuberculosis (TB) in animal models. However, their role in human immunity …

Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity

NP Kumar, KF Fukutani, BS Shruthi, T Alves… - Elife, 2019 - elifesciences.org
Diabetes mellitus (DM) increases risk for pulmonary tuberculosis (TB) and adverse treatment
outcomes. Systemic hyper-inflammation is characteristic in people with TB and concurrent …

Immunologic, metabolic and genetic impact of diabetes on tuberculosis susceptibility

P Ssekamatte, OJ Sande, R Van Crevel… - Frontiers in …, 2023 - frontiersin.org
Due to the increasing prevalence of diabetes mellitus (DM) globally, the interaction between
DM and major global diseases like tuberculosis (TB) is of great public health significance …

Heme oxygenase-1 determines the cell fate of ferroptotic death of alveolar macrophages in COPD

Y Li, Y Yang, T Guo, C Weng, Y Yang, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Background Despite an increasing understanding of chronic obstructive pulmonary disease
(COPD) pathogenesis, the mechanisms of diverse cell populations in the human lung …

Impact of diabetes mellitus on immunity to latent tuberculosis infection

NP Kumar, S Babu - Frontiers in Clinical Diabetes and Healthcare, 2023 - frontiersin.org
Tuberculosis (TB) is an infectious disease that poses a major health threat and is one of the
leading causes of death worldwide. Following exposure to Mycobacterium tuberculosis (M …

Histone deacetylase 6 inhibitor enhances resistance to Mycobacterium tuberculosis infection through innate and adaptive immunity in mice

X Wang, X Tang, Z Zhou, Q Huang - Pathogens and disease, 2018 - academic.oup.com
Abstract Interleukin (IL)-10 plays a key role in immune response following mycobacterial
infection, which can be inhibited by histone deacetylase (HDAC) 6. In this study, we …