Insights into the binding of dietary phenolic compounds to human serum albumin and food-drug interactions
A López-Yerena, M Perez, A Vallverdú-Queralt… - Pharmaceutics, 2020 - mdpi.com
The distribution of drugs and dietary phenolic compounds in the systemic circulation de-
pends on, among other factors, unspecific/specific reversible binding to plasma proteins …
pends on, among other factors, unspecific/specific reversible binding to plasma proteins …
Drug-food interactions with a focus on Mediterranean diet
There is a growing interest among people in western countries for adoption of healthier
lifestyle habits and diet behaviors with one of the most known ones to be Mediterranean diet …
lifestyle habits and diet behaviors with one of the most known ones to be Mediterranean diet …
Influence of antioxidant flavonoids quercetin and rutin on the in-vitro binding of neratinib to human serum albumin
This study was designed to examine the interaction of neratinib (NRB) with human serum
albumin (HSA) in presence of flavonoids quercetin and rutin. Both quercetin and rutin can …
albumin (HSA) in presence of flavonoids quercetin and rutin. Both quercetin and rutin can …
[HTML][HTML] Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and …
H Kaci, S Bodnárová, E Fliszár-Nyúl, B Lemli… - Biomedicine & …, 2023 - Elsevier
Luteolin and naringenin are flavonoids found in various foods/beverages and present in
certain dietary supplements. After a high intake of these flavonoids, their sulfate and …
certain dietary supplements. After a high intake of these flavonoids, their sulfate and …
[HTML][HTML] Concomitant binding of two fluorescent probes at site-I of human serum albumin: The protein acting as a scaffold enabling fluorescence resonance energy …
VF Ximenes - Journal of Photochemistry and Photobiology B: Biology, 2022 - Elsevier
Human serum albumin (HSA) is the primary drug carrier in the blood plasma. Here, I aimed
to show that two ligands can be accommodated simultaneously in the binding site-I of HSA …
to show that two ligands can be accommodated simultaneously in the binding site-I of HSA …
Interaction of mycotoxin alternariol with serum albumin
E Fliszár-Nyúl, B Lemli, S Kunsági-Máté… - International journal of …, 2019 - mdpi.com
Alternariol (AOH) is a mycotoxin produced by Alternaria species. In vitro studies suggest the
genotoxic, mutagenic, and endocrine disruptor effects of AOH, and an increased incidence …
genotoxic, mutagenic, and endocrine disruptor effects of AOH, and an increased incidence …
Molecular basis of interactions between the antibiotic nitrofurantoin and human serum albumin: a mechanism for the rapid drug blood transportation
Nitrofurantoin is an antimicrobial agent obtained through the addition of a nitro group and a
side chain containing hydantoin to a furan ring. The interactions of the antibiotic with human …
side chain containing hydantoin to a furan ring. The interactions of the antibiotic with human …
Hydrochlorothiazide binding to human serum albumin induces some compactness in the molecular structure of the protein: a multi-spectroscopic and computational …
F Balaei, S Ghobadi - Journal of pharmaceutical and biomedical analysis, 2019 - Elsevier
The interaction between hydrochlorothiazide (HCTZ), a diuretic drug, with human serum
albumin (HSA) was investigated by different biophysical approaches such as UV absorption …
albumin (HSA) was investigated by different biophysical approaches such as UV absorption …
[HTML][HTML] Interactions of casticin, ipriflavone, and resveratrol with serum albumin and their inhibitory effects on CYP2C9 and CYP3A4 enzymes
Polyphenols are abundant molecules in the plant kingdom. They interact with several
proteins in the body resulting in their complex biological effects. Previous studies …
proteins in the body resulting in their complex biological effects. Previous studies …
Chiral Au (III) chelates exhibit unique NCI-60 cytotoxicity profiles and interactions with human serum albumin
Au (III) bis (pyrrolide-imine) chelates are emerging as a class of versatile, efficacious
metallodrug candidates. Here, we synthesised two enantiopure chiral ligands H2L1 and …
metallodrug candidates. Here, we synthesised two enantiopure chiral ligands H2L1 and …