Insights into the binding of dietary phenolic compounds to human serum albumin and food-drug interactions

A López-Yerena, M Perez, A Vallverdú-Queralt… - Pharmaceutics, 2020 - mdpi.com
The distribution of drugs and dietary phenolic compounds in the systemic circulation de-
pends on, among other factors, unspecific/specific reversible binding to plasma proteins …

Drug-food interactions with a focus on Mediterranean diet

M Spanakis, E Patelarou, A Patelarou - Applied Sciences, 2022 - mdpi.com
There is a growing interest among people in western countries for adoption of healthier
lifestyle habits and diet behaviors with one of the most known ones to be Mediterranean diet …

Influence of antioxidant flavonoids quercetin and rutin on the in-vitro binding of neratinib to human serum albumin

TA Wani, AH Bakheit, S Zargar, ZS Alanazi… - … Acta Part A: Molecular …, 2021 - Elsevier
This study was designed to examine the interaction of neratinib (NRB) with human serum
albumin (HSA) in presence of flavonoids quercetin and rutin. Both quercetin and rutin can …

[HTML][HTML] Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and …

H Kaci, S Bodnárová, E Fliszár-Nyúl, B Lemli… - Biomedicine & …, 2023 - Elsevier
Luteolin and naringenin are flavonoids found in various foods/beverages and present in
certain dietary supplements. After a high intake of these flavonoids, their sulfate and …

[HTML][HTML] Concomitant binding of two fluorescent probes at site-I of human serum albumin: The protein acting as a scaffold enabling fluorescence resonance energy …

VF Ximenes - Journal of Photochemistry and Photobiology B: Biology, 2022 - Elsevier
Human serum albumin (HSA) is the primary drug carrier in the blood plasma. Here, I aimed
to show that two ligands can be accommodated simultaneously in the binding site-I of HSA …

Interaction of mycotoxin alternariol with serum albumin

E Fliszár-Nyúl, B Lemli, S Kunsági-Máté… - International journal of …, 2019 - mdpi.com
Alternariol (AOH) is a mycotoxin produced by Alternaria species. In vitro studies suggest the
genotoxic, mutagenic, and endocrine disruptor effects of AOH, and an increased incidence …

Molecular basis of interactions between the antibiotic nitrofurantoin and human serum albumin: a mechanism for the rapid drug blood transportation

A Calderaro, A Maugeri, S Magazù, G Laganà… - International Journal of …, 2021 - mdpi.com
Nitrofurantoin is an antimicrobial agent obtained through the addition of a nitro group and a
side chain containing hydantoin to a furan ring. The interactions of the antibiotic with human …

Hydrochlorothiazide binding to human serum albumin induces some compactness in the molecular structure of the protein: a multi-spectroscopic and computational …

F Balaei, S Ghobadi - Journal of pharmaceutical and biomedical analysis, 2019 - Elsevier
The interaction between hydrochlorothiazide (HCTZ), a diuretic drug, with human serum
albumin (HSA) was investigated by different biophysical approaches such as UV absorption …

[HTML][HTML] Interactions of casticin, ipriflavone, and resveratrol with serum albumin and their inhibitory effects on CYP2C9 and CYP3A4 enzymes

V Mohos, T Bencsik, G Boda, E Fliszár-Nyúl… - Biomedicine & …, 2018 - Elsevier
Polyphenols are abundant molecules in the plant kingdom. They interact with several
proteins in the body resulting in their complex biological effects. Previous studies …

Chiral Au (III) chelates exhibit unique NCI-60 cytotoxicity profiles and interactions with human serum albumin

S Sookai, MP Akerman, OQ Munro - Dalton Transactions, 2024 - pubs.rsc.org
Au (III) bis (pyrrolide-imine) chelates are emerging as a class of versatile, efficacious
metallodrug candidates. Here, we synthesised two enantiopure chiral ligands H2L1 and …