[HTML][HTML] Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli

M Desvaux, G Dalmasso, R Beyrouthy… - Frontiers in …, 2020 - frontiersin.org
Escherichia coli is a versatile bacterial species that includes both harmless commensal
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …

E. coli as an All-Rounder: The Thin Line Between Commensalism and Pathogenicity

A Leimbach, J Hacker, U Dobrindt - Between pathogenicity and …, 2013 - Springer
Escherichia coli is a paradigm for a versatile bacterial species which comprises harmless
commensal as well as different pathogenic variants with the ability to either cause intestinal …

[HTML][HTML] High Prevalence of Mucosa-Associated E. coli Producing Cyclomodulin and Genotoxin in Colon Cancer

E Buc, D Dubois, P Sauvanet, J Raisch, J Delmas… - PloS one, 2013 - journals.plos.org
Some Escherichia coli strains produce toxins designated cyclomodulins (CMs) which
interfere with the eukaryotic cell cycle of host cells, suggesting a possible link between these …

[HTML][HTML] Gut microbiota and colorectal cancer

R Gao, Z Gao, L Huang, H Qin - European Journal of Clinical Microbiology …, 2017 - Springer
The gut microbiota is considered as a forgotten organ in human health and disease. It
maintains gut homeostasis by various complex mechanisms. However, disruption of the gut …

Molecular Diversity of Escherichia Coli in the Human Gut: New Ecological Evidence Supporting the Role of Adherent-Invasive E. Coli (AIEC) in Crohn's disease

M Martinez-Medina, X Aldeguer… - Inflammatory bowel …, 2009 - academic.oup.com
Background Escherichia coli, particularly the adherent-invasive E. coli (AIEC) pathovar, has
been increasingly implicated in the ethiopathogenesis of Crohn's disease (CD). We describe …

Genetic Structure and Distribution of the Colibactin Genomic Island among Members of the Family Enterobacteriaceae

J Putze, C Hennequin, JP Nougayrede… - Infection and …, 2009 - Am Soc Microbiol
ABSTRACT A genomic island encoding the biosynthesis and secretion pathway of putative
hybrid nonribosomal peptide-polyketide colibactin has been recently described in …

Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases

CN Bernstein, F Shanahan - Gut, 2008 - gut.bmj.com
Few would contest that advances in uncovering genetic risk factors for Crohn's disease and
ulcerative colitis over the past decade have changed the way we think about inflammatory …

[HTML][HTML] Complete Genome Sequence of Crohn's Disease-Associated Adherent-Invasive E. coli Strain LF82

S Miquel, E Peyretaillade, L Claret, A De Vallée… - PloS one, 2010 - journals.plos.org
Background Ileal lesions of Crohn's disease (CD) patients are abnormally colonized by
pathogenic adherent-invasive Escherichia coli (AIEC) able to invade and to replicate within …

Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancer

A Boleij, H Tjalsma - Biological Reviews, 2012 - Wiley Online Library
A healthy human body contains at least tenfold more bacterial cells than human cells and
the most abundant and diverse microbial community resides in the intestinal tract. Intestinal …

Human intestinal microbiota: cross-talk with the host and its potential role in colorectal cancer

M Candela, M Guidotti, A Fabbri, P Brigidi… - Critical reviews in …, 2011 - Taylor & Francis
In this review, we discuss the multifactorial role of intestinal microbiota in colorectal cancer.
The peculiar metabolism of dietary compounds of the individual microbiota complement, its …